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Tmem45a transmembrane protein 45a [ Mus musculus (house mouse) ]

Gene ID: 56277, updated on 26-Sep-2022

Summary

Official Symbol
Tmem45aprovided by MGI
Official Full Name
transmembrane protein 45aprovided by MGI
Primary source
MGI:MGI:1913122
See related
Ensembl:ENSMUSG00000022754 AllianceGenome:MGI:1913122
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
p19.5; C630002M10Rik
Summary
Predicted to be integral component of plasma membrane. Is expressed in forelimb and genitourinary system. Orthologous to human TMEM45A (transmembrane protein 45A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in limb E14.5 (RPKM 6.4), bladder adult (RPKM 2.9) and 13 other tissues See more
Orthologs
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Genomic context

See Tmem45a in Genome Data Viewer
Location:
16; 16 C1.1
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (56625524..56706648, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (56805161..56886433, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene Trk-fused gene Neighboring gene adhesion G protein-coupled receptor G7 Neighboring gene predicted gene 15693 Neighboring gene programmed cell death 6 interacting protein pseudogene Neighboring gene leukemia NUP98 fusion partner 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 

General protein information

Preferred Names
transmembrane protein 45A
Names
19.5 mRNA
dermal papilla-derived protein 7 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019631.3NP_062605.2  transmembrane protein 45A

    See identical proteins and their annotated locations for NP_062605.2

    Status: PROVISIONAL

    Source sequence(s)
    AK049837
    Consensus CDS
    CCDS28226.1
    UniProtKB/TrEMBL
    Q8BFU6
    Related
    ENSMUSP00000023435.6, ENSMUST00000023435.6
    Conserved Domains (1) summary
    pfam04819
    Location:121238
    DUF716; Family of unknown function (DUF716)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    56625524..56706648 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006522395.5XP_006522458.1  transmembrane protein 45A isoform X1

    See identical proteins and their annotated locations for XP_006522458.1

    Conserved Domains (1) summary
    pfam04819
    Location:121238
    DUF716; Family of unknown function (DUF716)
  2. XM_030249197.2XP_030105057.1  transmembrane protein 45A isoform X2

    UniProtKB/TrEMBL
    Q8BFU6
    Conserved Domains (1) summary
    pfam04819
    Location:121238
    DUF716; Family of unknown function (DUF716)
  3. XM_006522396.4XP_006522459.1  transmembrane protein 45A isoform X1

    See identical proteins and their annotated locations for XP_006522459.1

    Conserved Domains (1) summary
    pfam04819
    Location:121238
    DUF716; Family of unknown function (DUF716)
  4. XM_036160036.1XP_036015929.1  transmembrane protein 45A isoform X2

    UniProtKB/TrEMBL
    Q8BFU6
    Conserved Domains (1) summary
    pfam04819
    Location:121238
    DUF716; Family of unknown function (DUF716)
  5. XM_036160035.1XP_036015928.1  transmembrane protein 45A isoform X1

    Conserved Domains (1) summary
    pfam04819
    Location:121238
    DUF716; Family of unknown function (DUF716)
  6. XM_030249196.2XP_030105056.1  transmembrane protein 45A isoform X2

    UniProtKB/TrEMBL
    Q8BFU6
    Conserved Domains (1) summary
    pfam04819
    Location:121238
    DUF716; Family of unknown function (DUF716)
  7. XM_017317086.2XP_017172575.1  transmembrane protein 45A isoform X1

    Conserved Domains (1) summary
    pfam04819
    Location:121238
    DUF716; Family of unknown function (DUF716)