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ppp2r5a protein phosphatase 2, regulatory subunit B', alpha isoform [ Danio rerio (zebrafish) ]

Gene ID: 562460, updated on 5-Jul-2025
Official Symbol
ppp2r5aprovided by ZNC
Official Full Name
protein phosphatase 2, regulatory subunit B', alpha isoformprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040724-174
See related
Ensembl:ENSDARG00000092853 AllianceGenome:ZFIN:ZDB-GENE-040724-174
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-18c8.1
Summary
Predicted to enable protein phosphatase activator activity. Predicted to act upstream of or within signal transduction. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytosol and nucleus. Orthologous to human PPP2R5A (protein phosphatase 2 regulatory subunit B'alpha). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
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Location:
chromosome: 20
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 20 NC_133195.1 (14412254..14548588)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 20 NC_007131.7 (13175586..13309554)

Chromosome 20 - NC_133195.1Genomic Context describing neighboring genes Neighboring gene integrator complex subunit 7 Neighboring gene uncharacterized LOC137488723 Neighboring gene denticleless E3 ubiquitin protein ligase homolog (Drosophila) Neighboring gene uncharacterized LOC137488715 Neighboring gene potassium channel, subfamily K, member 3a Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 1

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables protein phosphatase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein phosphatase regulator activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of protein phosphatase type 2A complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of protein phosphatase type 2A complex IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

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RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133195.1 Reference GRCz12tu Primary Assembly

    Range
    14412254..14548588
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005160442.6XP_005160499.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

    UniProtKB/TrEMBL
    A0A8M2B7J5
    Conserved Domains (3) summary
    PLN00122
    Location:359453
    PLN00122; serine/threonine protein phosphatase 2A; Provisional
    pfam01603
    Location:55453
    B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    cl14852
    Location:135227
    WYL; WYL domain