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enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 [ Danio rerio (zebrafish) ]

Gene ID: 562399, updated on 17-Nov-2020

Summary

Official Symbol
enpp1provided by ZNC
Official Full Name
ectonucleotide pyrophosphatase/phosphodiesterase 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040724-172
See related
Ensembl:ENSDARG00000005789
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:136238; si:ch211-142e24.2
Orthologs

Genomic context

See enpp1 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
26
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (13403214..13521014)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (13507257..13625034)
103 previous assembly Zv9 (GCF_000002035.4) 20 NC_007131.5 (13317988..13435857)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101886508 Neighboring gene protein phosphatase 2, regulatory subunit B', alpha isoform Neighboring gene potassium channel, subfamily K, member 3a Neighboring gene synaptotagmin-like 3 Neighboring gene ezrin b Neighboring gene radial spoke head 3

Genomic regions, transcripts, and products

Bibliography

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC136238

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide diphosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphodiesterase I activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
ATP metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
inorganic diphosphate transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of fat cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleoside triphosphate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphate ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of bone mineralization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of bone mineralization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ectonucleotide pyrophosphatase/phosphodiesterase family member 1
Names
dgf
NP_001025339.1
XP_005160498.1
XP_009292877.1
XP_021324146.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030168.1NP_001025339.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 1

    Status: PROVISIONAL

    Source sequence(s)
    BX293547
    Conserved Domains (5) summary
    smart00201
    Location:112155
    SO; Somatomedin B -like domains
    pfam01033
    Location:70108
    Somatomedin_B; Somatomedin B domain
    pfam01663
    Location:179505
    Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase
    cd16018
    Location:177545
    Enpp; Ectonucleotide pyrophosphatase/phosphodiesterase, also called autotaxin
    cl00089
    Location:642860
    NUC; DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases. They exists as monomers and homodimers.

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    13403214..13521014
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009294602.3XP_009292877.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform X2

    Conserved Domains (4) summary
    pfam01033
    Location:70108
    Somatomedin_B; Somatomedin B domain
    pfam01663
    Location:137463
    Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase
    cd16018
    Location:135503
    Enpp; Ectonucleotide pyrophosphatase/phosphodiesterase, also called autotaxin
    cl00089
    Location:602820
    NUC; DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases. They exists as monomers and homodimers.
  2. XM_005160441.4XP_005160498.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform X1

    See identical proteins and their annotated locations for XP_005160498.1

    UniProtKB/TrEMBL
    B0JZL7
    Related
    ENSDARP00000112341.3, ENSDART00000127350.4
    Conserved Domains (5) summary
    smart00201
    Location:112155
    SO; Somatomedin B -like domains
    pfam01033
    Location:70108
    Somatomedin_B; Somatomedin B domain
    pfam01663
    Location:179505
    Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase
    cd16018
    Location:177545
    Enpp; Ectonucleotide pyrophosphatase/phosphodiesterase, also called autotaxin
    cl00089
    Location:644862
    NUC; DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases. They exists as monomers and homodimers.
  3. XM_021468471.1XP_021324146.1  ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform X3

    Conserved Domains (4) summary
    smart00201
    Location:112155
    SO; Somatomedin B -like domains
    pfam01033
    Location:70108
    Somatomedin_B; Somatomedin B domain
    pfam01663
    Location:179505
    Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase
    cl00089
    Location:644740
    NUC; DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases. They exists as monomers and homodimers.
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