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prkdc protein kinase, DNA-activated, catalytic subunit [ Danio rerio (zebrafish) ]

Gene ID: 562283, updated on 12-Aug-2018

Summary

Official Symbol
prkdcprovided by ZNC
Official Full Name
protein kinase, DNA-activated, catalytic subunitprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-9008
See related
Ensembl:ENSDARG00000075083 Vega:OTTDARG00000043953
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
fa96e12; wu:fa96e12
Orthologs

Genomic context

See prkdc in Genome Data Viewer
Location:
chromosome: 7
Exon count:
86
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (41348723..41396811, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (41068650..41116738, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene neutrophil cytosolic factor 2 Neighboring gene GRB2 associated, regulator of MAPK1 Neighboring gene ATP-binding cassette, sub-family F (GCN20), member 2b Neighboring gene chondroitin polymerizing factor 2

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-dependent protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
B cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
DNA repair IEA
Inferred from Electronic Annotation
more info
 
T cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
T cell receptor V(D)J recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to DNA damage stimulus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
double-strand break repair IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
double-strand break repair via nonhomologous end joining IEA
Inferred from Electronic Annotation
more info
 
immunoglobulin V(D)J recombination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
immunoglobulin V(D)J recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
immunoglobulin heavy chain V-D-J recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
intrinsic apoptotic signaling pathway in response to DNA damage IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
telomere maintenance IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
DNA-dependent protein kinase catalytic subunit
Names
protein kinase, DNA-activated, catalytic polypeptide
XP_009301676.1

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    41348723..41396811 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009303401.2XP_009301676.1  DNA-dependent protein kinase catalytic subunit

    UniProtKB/TrEMBL
    E7F4J7
    Related
    ENSDARP00000051678.4, OTTDARP00000049997, ENSDART00000051679.8, OTTDART00000063950
    Conserved Domains (4) summary
    cd05172
    Location:37134006
    PIKKc_DNA-PK; Catalytic domain of DNA-dependent protein kinase
    pfam02259
    Location:30703465
    FAT; FAT domain
    pfam02260
    Location:40894119
    FATC; FATC domain
    pfam08163
    Location:18302211
    NUC194; NUC194 domain
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