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aimp1a aminoacyl tRNA synthetase complex interacting multifunctional protein 1a [ Danio rerio (zebrafish) ]

Gene ID: 562232, updated on 9-Sep-2025
Official Symbol
aimp1aprovided by ZNC
Official Full Name
aminoacyl tRNA synthetase complex interacting multifunctional protein 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060825-144
See related
Ensembl:ENSDARG00000060036 AllianceGenome:ZFIN:ZDB-GENE-060825-144
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
aimp1; wu:fa95a05; zgc:154081
Summary
Predicted to enable tRNA binding activity. Is expressed in several structures, including brain; digestive system; optic cup; pectoral fin bud; and swim bladder. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 3. Orthologous to human AIMP1 (aminoacyl tRNA synthetase complex interacting multifunctional protein 1). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
human mouse all
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See aimp1a in Genome Data Viewer
Location:
chromosome: 1
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 1 NC_133176.1 (53610881..53636632)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 1 NC_007112.7 (50293979..50319654)

Chromosome 1 - NC_133176.1Genomic Context describing neighboring genes Neighboring gene glutathione S-transferase, C-terminal domain containing Neighboring gene sphingomyelin synthase 2a Neighboring gene nephronectin a Neighboring gene TBC1 domain containing kinase Neighboring gene dickkopf WNT signaling pathway inhibitor 2 Neighboring gene 3'-phosphoadenosine 5'-phosphosulfate synthase 1

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. Systematic expression profiling of neuropathy-related aminoacyl-tRNA synthetases in zebrafish during development. Giong HK, et al. Biochem Biophys Res Commun, 2022 Jan 8. PMID 34872004
  2. A transcriptomics analysis of the Tbx5 paralogues in zebrafish. Boyle Anderson EAT, et al. PLoS One, 2018. PMID 30532148, Free PMC Article
  3. Biallelic variants in KARS1 are associated with neurodevelopmental disorders and hearing loss recapitulated by the knockout zebrafish. Lin SJ, et al. Genet Med, 2021 Oct. PMID 34172899, Free PMC Article
  4. MicroRNA-223 Suppresses the Canonical NF-κB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation. Zhou W, et al. Cell Rep, 2018 Feb 13. PMID 29444433, Free PMC Article
  5. Identification and Expression Analysis of the Complete Family of Zebrafish pkd Genes. England SJ, et al. Front Cell Dev Biol, 2017. PMID 28271061, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Clone Names

  • MGC154081

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables tRNA binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
aminoacyl tRNA synthase complex-interacting multifunctional protein 1a
Names
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045851.1 → NP_001039316.1  aminoacyl tRNA synthase complex-interacting multifunctional protein 1a

    See identical proteins and their annotated locations for NP_001039316.1

    Status: PROVISIONAL

    Source sequence(s)
    BC122449
    UniProtKB/TrEMBL
    Q0P3U2
    Related
    ENSDARP00000078619.4, ENSDART00000084184.5
    Conserved Domains (2) summary
    cd02799
    Location:153 → 255
    tRNA_bind_EMAP-II_like; tRNA-binding-domain-containing EMAP2-like proteins. This family contains a diverse fraction of tRNA binding proteins, including Caenorhabditis elegans methionyl-tRNA synthetase (CeMetRS), human tyrosyl- tRNA synthetase (hTyrRS), Saccharomyces cerevisiae ...
    cl21478
    Location:5 → 81
    ATP-synt_B; ATP synthase B/B' CF(0)

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133176.1 Reference GRCz12tu Primary Assembly

    Range
    53610881..53636632
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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