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PRKY protein kinase Y-linked (pseudogene) [ Homo sapiens (human) ]

Gene ID: 5616, updated on 8-Dec-2022

Summary

Official Symbol
PRKYprovided by HGNC
Official Full Name
protein kinase Y-linked (pseudogene)provided by HGNC
Primary source
HGNC:HGNC:9444
See related
Ensembl:ENSG00000099725 MIM:400008; AllianceGenome:HGNC:9444
Gene type
pseudo
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRKYP; PRKXP3
Summary
This gene is similar to the protein kinase, X-linked gene in the pseudoautosomal region of the X chromosome. The gene is classified as a transcribed pseudogene because it has lost a coding exon that results in all transcripts being candidates for nonsense-mediated decay (NMD) and unlikely to express a protein. Abnormal recombination between this gene and a related gene on chromosome X is a frequent cause of XX males and XY females. [provided by RefSeq, Jul 2010]
Expression
Broad expression in skin (RPKM 2.8), prostate (RPKM 1.9) and 19 other tissues See more
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Genomic context

See PRKY in Genome Data Viewer
Location:
Yp11.2
Exon count:
8
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) Y NC_000024.10 (7273972..7381547)
110 current T2T-CHM13v2.0 (GCF_009914755.1) Y NC_060948.1 (6926299..7033870)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) Y NC_000024.9 (7142013..7249588)

Chromosome Y - NC_000024.10Genomic Context describing neighboring genes Neighboring gene transducin beta like 1 Y-linked Neighboring gene family with sequence similarity 199, Y-linked, pseudogene Neighboring gene G protein-coupled receptor 143 pseudogene Neighboring gene RN7SK pseudogene 282 Neighboring gene RNA, U6 small nuclear 941, pseudogene Neighboring gene RNA, U6 small nuclear 521, pseudogene Neighboring gene uncharacterized LOC107987338

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables protein serine kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation TAS
Traceable Author Statement
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_028062.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AA767129, AC007284, AC010143, BC074852, Y15801
    Related
    ENST00000528056.5

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000024.10 Reference GRCh38.p14 Primary Assembly

    Range
    7273972..7381547
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060948.1 Alternate T2T-CHM13v2.0

    Range
    6926299..7033870
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_002760.3: Suppressed sequence

    Description
    NM_002760.3: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.