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TEX11 testis expressed 11 [ Homo sapiens (human) ]

Gene ID: 56159, updated on 12-Aug-2018
Official Symbol
TEX11provided by HGNC
Official Full Name
testis expressed 11provided by HGNC
Primary source
HGNC:HGNC:11733
See related
Ensembl:ENSG00000120498 MIM:300311; Vega:OTTHUMG00000021782
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TGC1; TSGA3; SPGFX2
Summary
This gene is X-linked and is expressed in only male germ cells. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Expression
Biased expression in pancreas (RPKM 5.2), testis (RPKM 5.1) and 1 other tissue See more
Orthologs
See TEX11 in Genome Data Viewer
Location:
Xq13.1
Exon count:
36
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) X NC_000023.11 (70511227..70908717, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (69748790..70128567, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene RNA, U4 small nuclear 81, pseudogene Neighboring gene DLG3 antisense RNA 1 Neighboring gene discs large MAGUK scaffold protein 3 Neighboring gene small integral membrane protein 30-like Neighboring gene WASH complex subunit 3 pseudogene Neighboring gene small nucleolar RNA, C/D box 3E Neighboring gene solute carrier family 7 member 3 Neighboring gene ribosomal protein S23 pseudogene 8

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
chiasma assembly IEA
Inferred from Electronic Annotation
more info
 
fertilization IEA
Inferred from Electronic Annotation
more info
 
male gonad development IEA
Inferred from Electronic Annotation
more info
 
male meiosis chromosome segregation IEA
Inferred from Electronic Annotation
more info
 
meiotic gene conversion ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
reciprocal meiotic recombination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
reciprocal meiotic recombination ISS
Inferred from Sequence or Structural Similarity
more info
 
resolution of meiotic recombination intermediates IEA
Inferred from Electronic Annotation
more info
 
synaptonemal complex assembly IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
central element IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with synaptonemal complex ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
testis-expressed protein 11
Names
testis expressed sequence 11
testis-expressed sequence 11 protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012574.1 RefSeqGene

    Range
    5001..384778
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001003811.1NP_001003811.1  testis-expressed protein 11 isoform 1

    See identical proteins and their annotated locations for NP_001003811.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK057523, BC036016, BG219070, BU929507
    Consensus CDS
    CCDS35323.1
    UniProtKB/Swiss-Prot
    Q8IYF3
    Related
    ENSP00000379226.2, OTTHUMP00000217425, ENST00000395889.6, OTTHUMT00000359072
    Conserved Domains (2) summary
    sd00006
    Location:417451
    TPR; TPR repeat [structural motif]
    pfam08631
    Location:190444
    SPO22; Meiosis protein SPO22/ZIP4 like
  2. NM_031276.2NP_112566.2  testis-expressed protein 11 isoform 2

    See identical proteins and their annotated locations for NP_112566.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an exon in the 5' region, as compared to variant 1. It uses an upstream in-frame AUG codon and encodes isoform 2 which has a shorter and distinct N-terminus, as compared to isoform 1.
    Source sequence(s)
    AK057391, AK057523, BC036016, BG219070, BU929507
    Consensus CDS
    CCDS43968.1
    UniProtKB/Swiss-Prot
    Q8IYF3
    Related
    ENSP00000363453.2, OTTHUMP00000023480, ENST00000374333.6, OTTHUMT00000057083
    Conserved Domains (2) summary
    sd00006
    Location:402436
    TPR; TPR repeat [structural motif]
    pfam08631
    Location:175429
    SPO22; Meiosis protein SPO22/ZIP4 like

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p12 Primary Assembly

    Range
    70511227..70908717 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017029649.1XP_016885138.1  testis-expressed protein 11 isoform X1

  2. XM_017029650.1XP_016885139.1  testis-expressed protein 11 isoform X3

  3. XM_017029651.1XP_016885140.1  testis-expressed protein 11 isoform X4

  4. XM_017029652.2XP_016885141.1  testis-expressed protein 11 isoform X6

  5. XM_011530994.1XP_011529296.1  testis-expressed protein 11 isoform X2

    Conserved Domains (2) summary
    sd00006
    Location:402436
    TPR; TPR repeat [structural motif]
    pfam08631
    Location:175429
    SPO22; Meiosis protein SPO22/ZIP4 like
  6. XM_011530996.1XP_011529298.1  testis-expressed protein 11 isoform X5

    UniProtKB/Swiss-Prot
    Q8IYF3
    Related
    ENSP00000363440.2, OTTHUMP00000023482, ENST00000374320.6, OTTHUMT00000057085
    Conserved Domains (2) summary
    sd00006
    Location:92126
    TPR; TPR repeat [structural motif]
    pfam08631
    Location:1119
    SPO22; Meiosis protein SPO22/ZIP4 like
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