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Psmg1 proteasome (prosome, macropain) assembly chaperone 1 [ Mus musculus (house mouse) ]

Gene ID: 56088, updated on 9-Mar-2023


Official Symbol
Psmg1provided by MGI
Official Full Name
proteasome (prosome, macropain) assembly chaperone 1provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000022913 AllianceGenome:MGI:1860263
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Enables proteasome binding activity. Acts upstream of or within cerebellar granule cell precursor proliferation and proteasome core complex assembly. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Predicted to be part of chaperone complex. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human PSMG1 (proteasome assembly chaperone 1). [provided by Alliance of Genome Resources, Apr 2022]
Ubiquitous expression in CNS E11.5 (RPKM 32.4), placenta adult (RPKM 19.0) and 27 other tissues See more
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Genomic context

See Psmg1 in Genome Data Viewer
16; 16 C4
Exon count:
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (95781133..95792160, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (95979933..95990960, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32130 Neighboring gene predicted gene, 41509 Neighboring gene RIKEN cDNA 1600002D24 gene Neighboring gene predicted gene, 41508 Neighboring gene bromodomain and WD repeat domain containing 1 Neighboring gene high mobility group nucleosomal binding domain 1

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a



Alleles of this type are documented at Mouse Genome Informatics  (MGI)


Products Interactant Other Gene Complex Source Pubs Description

General gene information



Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular adaptor activity ISO
Inferred from Sequence Orthology
more info
enables proteasome binding IBA
Inferred from Biological aspect of Ancestor
more info
enables proteasome binding IDA
Inferred from Direct Assay
more info
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
located_in cytosol ISO
Inferred from Sequence Orthology
more info
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
part_of protein folding chaperone complex ISO
Inferred from Sequence Orthology
more info

General protein information

Preferred Names
proteasome assembly chaperone 1
Down syndrome critical region homolog 2
down syndrome critical region protein 2 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019537.3NP_062410.1  proteasome assembly chaperone 1

    See identical proteins and their annotated locations for NP_062410.1

    Status: VALIDATED

    Source sequence(s)
    BC032965, BG086724
    Consensus CDS
    Q8BU12, Q9JK23
    ENSMUSP00000023630.8, ENSMUST00000023630.16
    Conserved Domains (1) summary
    PAC1; Proteasome assembly chaperone 4

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000082.7 Reference GRCm39 C57BL/6J

    95781133..95792160 complement
    GenBank, FASTA, Sequence Viewer (Graphics)