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Dnah10 dynein, axonemal, heavy chain 10 [ Mus musculus (house mouse) ]

Gene ID: 56087, updated on 10-Oct-2019

Summary

Official Symbol
Dnah10provided by MGI
Official Full Name
dynein, axonemal, heavy chain 10provided by MGI
Primary source
MGI:MGI:1860299
See related
Ensembl:ENSMUSG00000038011
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Dnahc10
Expression
Biased expression in testis adult (RPKM 4.7), lung adult (RPKM 1.5) and 1 other tissue See more
Orthologs

Genomic context

See Dnah10 in Genome Data Viewer
Location:
5; 5 F
Exon count:
79
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (124725085..124834308)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (125205455..125314678)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene tectonic family member 2 Neighboring gene ATPase, H+ transporting, lysosomal V0 subunit A2 Neighboring gene coiled-coil domain containing 92 Neighboring gene zinc finger protein 664

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from BioSystems

  • Huntington's disease, organism-specific biosystem (from KEGG)
    Huntington's disease, organism-specific biosystemHuntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). The symptoms are choreiform, involuntary movements, personality...
  • Huntington's disease, conserved biosystem (from KEGG)
    Huntington's disease, conserved biosystemHuntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). The symptoms are choreiform, involuntary movements, personality...

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP-dependent microtubule motor activity, minus-end-directed IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dynein intermediate chain binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dynein light intermediate chain binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule motor activity IC
Inferred by Curator
more info
PubMed 
Process Evidence Code Pubs
cilium movement IC
Inferred by Curator
more info
PubMed 
microtubule-based movement IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
axoneme IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dynein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
inner dynein arm ISM
Inferred from Sequence Model
more info
PubMed 

General protein information

Preferred Names
dynein heavy chain 10, axonemal
Names
dynein, axon, heavy chain 10

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019536.1NP_062409.1  dynein heavy chain 10, axonemal

    Status: PROVISIONAL

    Source sequence(s)
    AC164649, AC242457
    Consensus CDS
    CCDS51649.1
    UniProtKB/TrEMBL
    D3YYQ8
    Related
    ENSMUSP00000062995.8, ENSMUST00000058440.11
    Conserved Domains (6) summary
    pfam03028
    Location:38844580
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08385
    Location:306878
    DHC_N1; Dynein heavy chain, N-terminal region 1
    pfam08393
    Location:13771780
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:31653498
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:35273743
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:19142142
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p6 C57BL/6J

    Range
    124725085..124834308
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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