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csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 [ Danio rerio (zebrafish) ]

Gene ID: 560826, updated on 9-Sep-2025
Official Symbol
csgalnact2provided by ZNC
Official Full Name
chondroitin sulfate N-acetylgalactosaminyltransferase 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5186
See related
Ensembl:ENSDARG00000061400 AllianceGenome:ZFIN:ZDB-GENE-030131-5186
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fb98d03; si:dkey-192p21.4; mp:zf637-2-001473
Summary
Predicted to enable glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Acts upstream of or within chondroitin sulfate proteoglycan biosynthetic process and heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi cisterna membrane. Is expressed in several structures, including cartilage element; nervous system; notochord; pronephric duct; and tail bud. Orthologous to human CSGALNACT2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
human mouse all
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See csgalnact2 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 13 NC_133188.1 (28787027..28801340, complement)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 13 NC_007124.7 (25568923..25583262, complement)

Chromosome 13 - NC_133188.1Genomic Context describing neighboring genes Neighboring gene minichromosome maintenance complex binding protein Neighboring gene SEC23 interacting protein Neighboring gene ret proto-oncogene receptor tyrosine kinase Neighboring gene si:dkey-192p21.6 Neighboring gene pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. Chondroitin/dermatan sulfate glycosyltransferase genes are essential for craniofacial development. Habicher J, et al. PLoS Genet, 2022 Feb. PMID 35192612, Free PMC Article
  2. Expression of chondroitin/dermatan sulfate glycosyltransferases during early zebrafish development. Filipek-Górniok B, et al. Dev Dyn, 2013 Aug. PMID 23703795
  3. On the roles and regulation of chondroitin sulfate and heparan sulfate in zebrafish pharyngeal cartilage morphogenesis. Holmborn K, et al. J Biol Chem, 2012 Sep 28. PMID 22869369, Free PMC Article
  4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables acetylgalactosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in chondroitin sulfate proteoglycan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within chondroitin sulfate proteoglycan biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within heparan sulfate proteoglycan biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
chondroitin sulfate N-acetylgalactosaminyltransferase 2
Names
zf637-2-001473
NP_001119869.1
XP_005156908.1
XP_073775725.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001126397.1 → NP_001119869.1  chondroitin sulfate N-acetylgalactosaminyltransferase 2

    See identical proteins and their annotated locations for NP_001119869.1

    Status: PROVISIONAL

    Source sequence(s)
    JBMGRA010000013
    UniProtKB/TrEMBL
    A0A8M1NHC5, A8E7C8
    Related
    ENSDARP00000081967.4, ENSDART00000087533.5
    Conserved Domains (1) summary
    cl11394
    Location:66 → 514
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133188.1 Reference GRCz12tu Primary Assembly

    Range
    28787027..28801340 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005156851.6 → XP_005156908.1  chondroitin sulfate N-acetylgalactosaminyltransferase 2 isoform X1

    See identical proteins and their annotated locations for XP_005156908.1

    UniProtKB/TrEMBL
    A0A8M1NHC5, A8E7C8
    Conserved Domains (1) summary
    cl11394
    Location:66 → 514
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

  2. XM_073919624.1 → XP_073775725.1  chondroitin sulfate N-acetylgalactosaminyltransferase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M1NHC5, A8E7C8

RNA

  1. XR_012388579.1 RNA Sequence

  2. XR_012388580.1 RNA Sequence

  3. XR_012388581.1 RNA Sequence

  4. XR_012388582.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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