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kmt2ca lysine (K)-specific methyltransferase 2Ca [ Danio rerio (zebrafish) ]

Gene ID: 560793, updated on 29-Apr-2017
Official Symbol
kmt2caprovided by ZNC
Official Full Name
lysine (K)-specific methyltransferase 2Caprovided by ZNC
Primary source
ZFIN:ZDB-GENE-080520-3
See related
Ensembl:ENSDARG00000079312 Vega:OTTDARG00000031784
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
mll3a; si:ch211-244o18.1; si:ch211-244o18.2
Orthologs
Location:
chromosome: 24
Exon count:
61
Annotation release Status Assembly Chr Location
105 current GRCz10 (GCF_000002035.5) 24 NC_007135.6 (7307683..7520242)
103 previous assembly Zv9 (GCF_000002035.4) 24 NC_007135.5 (7450296..7662967)

Chromosome 24 - NC_007135.6Genomic Context describing neighboring genes Neighboring gene ARP3 actin related protein 3 homolog B Neighboring gene X-ray repair complementing defective repair in Chinese hamster cells 2 Neighboring gene si:ch211-271e10.1 Neighboring gene UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
histone-lysine N-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
methylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
histone-lysine N-methyltransferase MLL3; histone-lysine N-methyltransferase 2C
Names
myeloid/lymphoid or mixed-lineage leukemia 3
myeloid/lymphoid or mixed-lineage leukemia 3a
XP_005162602.1
XP_005162603.1
XP_005162604.1
XP_005162605.1
XP_017209413.1
XP_017209414.1

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz10 Primary Assembly

Genomic

  1. NC_007135.6 Reference GRCz10 Primary Assembly

    Range
    7307683..7520242
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017353925.1XP_017209414.1  histone-lysine N-methyltransferase 2C isoform X3

  2. XM_017353924.1XP_017209413.1  histone-lysine N-methyltransferase 2C isoform X2

  3. XM_005162545.3XP_005162602.1  histone-lysine N-methyltransferase 2C isoform X1

    Conserved Domains (13) summary
    smart00398
    Location:17071760
    HMG; high mobility group
    smart00317
    Location:48194940
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    smart00508
    Location:49424958
    PostSET; Cysteine-rich motif following a subset of SET domains
    COG2940
    Location:48204958
    SET; SET domain-containing protein (function unknown) [General function prediction only]
    cd15509
    Location:360404
    PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
    cd15513
    Location:10301076
    PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
    cd15594
    Location:406451
    PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
    cd15596
    Location:9731029
    PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
    cd15697
    Location:44404544
    ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
    pfam04487
    Location:25862683
    CITED; CITED
    pfam05964
    Location:45994649
    FYRN; F/Y-rich N-terminus
    pfam05965
    Location:46564736
    FYRC; F/Y rich C-terminus
    cl22851
    Location:263346
    PHD_SF; PHD finger superfamily
  4. XM_005162546.3XP_005162603.1  histone-lysine N-methyltransferase 2C isoform X4

    UniProtKB/TrEMBL
    A0A0R4IM21
    Related
    ENSDARP00000137245.1, ENSDART00000162954.1
    Conserved Domains (13) summary
    smart00398
    Location:17071760
    HMG; high mobility group
    smart00317
    Location:48154936
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    smart00508
    Location:49384954
    PostSET; Cysteine-rich motif following a subset of SET domains
    COG2940
    Location:47474954
    SET; SET domain-containing protein (function unknown) [General function prediction only]
    cd15509
    Location:360404
    PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
    cd15513
    Location:10301076
    PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
    cd15594
    Location:406451
    PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
    cd15596
    Location:9731029
    PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
    cd15697
    Location:44404544
    ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
    pfam04487
    Location:25862683
    CITED; CITED
    pfam05964
    Location:45994649
    FYRN; F/Y-rich N-terminus
    pfam05965
    Location:46564736
    FYRC; F/Y rich C-terminus
    cl22851
    Location:263346
    PHD_SF; PHD finger superfamily
  5. XM_005162547.3XP_005162604.1  histone-lysine N-methyltransferase 2C isoform X5

    Related
    ENSDARP00000115827.2, OTTDARP00000035057, ENSDART00000137010.3, OTTDART00000044291
    Conserved Domains (13) summary
    smart00398
    Location:16911744
    HMG; high mobility group
    smart00317
    Location:48034924
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    smart00508
    Location:49264942
    PostSET; Cysteine-rich motif following a subset of SET domains
    COG2940
    Location:48044942
    SET; SET domain-containing protein (function unknown) [General function prediction only]
    cd15509
    Location:360404
    PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
    cd15513
    Location:10301076
    PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
    cd15594
    Location:406451
    PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
    cd15596
    Location:9731029
    PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
    cd15697
    Location:44244528
    ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
    pfam04487
    Location:25702667
    CITED; CITED
    pfam05964
    Location:45834633
    FYRN; F/Y-rich N-terminus
    pfam05965
    Location:46404720
    FYRC; F/Y rich C-terminus
    cl22851
    Location:263346
    PHD_SF; PHD finger superfamily
  6. XM_005162548.3XP_005162605.1  histone-lysine N-methyltransferase 2C isoform X6

    Conserved Domains (13) summary
    smart00398
    Location:16671720
    HMG; high mobility group
    smart00317
    Location:47794900
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    smart00508
    Location:49024918
    PostSET; Cysteine-rich motif following a subset of SET domains
    COG2940
    Location:47804918
    SET; SET domain-containing protein (function unknown) [General function prediction only]
    cd15509
    Location:360404
    PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
    cd15513
    Location:9901036
    PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
    cd15594
    Location:406451
    PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
    cd15596
    Location:933989
    PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
    cd15697
    Location:44004504
    ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
    pfam04487
    Location:25462643
    CITED; CITED
    pfam05964
    Location:45594609
    FYRN; F/Y-rich N-terminus
    pfam05965
    Location:46164696
    FYRC; F/Y rich C-terminus
    cl22851
    Location:263346
    PHD_SF; PHD finger superfamily
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