xdh xanthine dehydrogenase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: xdhprovided by ZNC
Official Full Name: xanthine dehydrogenaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-070719-9
See related: Ensembl:ENSDARG00000055240 AllianceGenome:ZFIN:ZDB-GENE-070719-9
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:7146167
Summary: Predicted to enable xanthine dehydrogenase activity. Predicted to be involved in xanthine catabolic process. Predicted to be located in peroxisome. Predicted to be active in extracellular space. Is expressed in neural crest cell and xanthoblast. Human ortholog(s) of this gene implicated in several diseases, including Lesch-Nyhan syndrome; cardiovascular system disease (multiple); chronic kidney disease; hyperuricemia; and xanthinuria. Orthologous to human XDH (xanthine dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (33340772..33374389)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (33388263..33421878)
103	previous assembly	Zv9 (GCF_000002035.4)	17	NC_007128.5 (33546510..33580048)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables 2 iron, 2 sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables FAD binding	IEA Inferred from Electronic Annotation more info
enables flavin adenine dinucleotide binding	IEA Inferred from Electronic Annotation more info
enables iron ion binding	IEA Inferred from Electronic Annotation more info
enables iron-sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables molybdenum ion binding	IEA Inferred from Electronic Annotation more info
enables molybdopterin cofactor binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables xanthine dehydrogenase activity	IBA Inferred from Biological aspect of Ancestor more info	PubMed
enables xanthine dehydrogenase activity	IEA Inferred from Electronic Annotation more info
enables xanthine oxidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in xanthine catabolic process	IBA Inferred from Biological aspect of Ancestor more info	PubMed

Component	Evidence Code	Pubs
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info	PubMed
located_in peroxisome	IEA Inferred from Electronic Annotation more info

XP_688983.3

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The following sections contain reference sequences that belong to a specific genome build. Explain