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Stard10 StAR related lipid transfer domain containing 10 [ Mus musculus (house mouse) ]

Gene ID: 56018, updated on 9-May-2024

Summary

Official Symbol
Stard10provided by MGI
Official Full Name
StAR related lipid transfer domain containing 10provided by MGI
Primary source
MGI:MGI:1860093
See related
Ensembl:ENSMUSG00000030688 AllianceGenome:MGI:1860093
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PCTP2; Pctpl; CGI-52; PC-TP2; TISP-81; NY-C0-28; Sdccag28; SdccagG28
Summary
Predicted to enable lipid binding activity. Acts upstream of or within bile acid secretion and positive regulation of peroxisome proliferator activated receptor signaling pathway. Located in several cellular components, including cytosol; intercellular canaliculus; and microvillus. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and liver and biliary system. Orthologous to human STARD10 (StAR related lipid transfer domain containing 10). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in liver adult (RPKM 468.9), colon adult (RPKM 328.7) and 14 other tissues See more
Orthologs
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Genomic context

See Stard10 in Genome Data Viewer
Location:
7 E2; 7 54.55 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (100966293..100995833)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (101317086..101346626)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene FCH and double SH3 domains 2 Neighboring gene predicted gene, 57508 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:108450776-108450959 Neighboring gene STARR-seq mESC enhancer starr_19689 Neighboring gene STARR-positive B cell enhancer ABC_E1349 Neighboring gene autophagy related 16 like 2 Neighboring gene predicted gene 20476 Neighboring gene STARR-seq mESC enhancer starr_19692 Neighboring gene STARR-positive B cell enhancer ABC_E4957 Neighboring gene predicted gene, 35219 Neighboring gene STARR-positive B cell enhancer ABC_E1740 Neighboring gene ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 Neighboring gene phosphodiesterase 2A, cGMP-stimulated Neighboring gene microRNA 139

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (4)  1 citation

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cilium IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in intercellular canaliculus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in intercellular canaliculus IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in microvillus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in microvillus IDA
Inferred from Direct Assay
more info
PubMed 
located_in motile cilium IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
START domain-containing protein 10
Names
PCTP-L
PCTP-like protein
START domain containing 10
serologically defined colon cancer antigen 10
serologically defined colon cancer antigen 28 homolog
stAR-related lipid transfer protein 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360460.1NP_001347389.1  START domain-containing protein 10 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC107638, AC129079
    Consensus CDS
    CCDS90281.1
    UniProtKB/TrEMBL
    E9PVP0, Q5RL65
    Related
    ENSMUSP00000129408.3, ENSMUST00000163799.9
    Conserved Domains (1) summary
    cd08871
    Location:92314
    START_STARD10-like; Lipid-binding START domain of mammalian STARD10 and related proteins
  2. NM_019990.5NP_064374.1  START domain-containing protein 10 isoform 2

    See identical proteins and their annotated locations for NP_064374.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AC129079
    Consensus CDS
    CCDS21509.1
    UniProtKB/Swiss-Prot
    Q9JMD3
    UniProtKB/TrEMBL
    Q0VG22, Q52LA1
    Related
    ENSMUSP00000032927.8, ENSMUST00000032927.14
    Conserved Domains (1) summary
    cd08871
    Location:19241
    START_STARD10-like; Lipid-binding START domain of mammalian STARD10 and related proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    100966293..100995833
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036153267.1XP_036009160.1  START domain-containing protein 10 isoform X1

    UniProtKB/Swiss-Prot
    Q9JMD3
    UniProtKB/TrEMBL
    Q0VG22, Q52LA1
    Conserved Domains (1) summary
    cd08871
    Location:19241
    START_STARD10-like; Lipid-binding START domain of mammalian STARD10 and related proteins
  2. XM_030242807.1XP_030098667.1  START domain-containing protein 10 isoform X1

    UniProtKB/Swiss-Prot
    Q9JMD3
    UniProtKB/TrEMBL
    Q0VG22, Q52LA1
    Related
    ENSMUSP00000133002.3, ENSMUST00000164479.9
    Conserved Domains (1) summary
    cd08871
    Location:19241
    START_STARD10-like; Lipid-binding START domain of mammalian STARD10 and related proteins