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Hebp2 heme binding protein 2 [ Mus musculus (house mouse) ]

Gene ID: 56016, updated on 5-Mar-2024

Summary

Official Symbol
Hebp2provided by MGI
Official Full Name
heme binding protein 2provided by MGI
Primary source
MGI:MGI:1860084
See related
Ensembl:ENSMUSG00000019853 AllianceGenome:MGI:1860084
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SOUL
Summary
Predicted to enable heme binding activity. Predicted to be involved in negative regulation of mitochondrial membrane potential; positive regulation of mitochondrial membrane permeability; and positive regulation of necrotic cell death. Located in cytoplasm. Orthologous to human HEBP2 (heme binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in bladder adult (RPKM 8.6), genital fat pad adult (RPKM 4.6) and 20 other tissues See more
Orthologs
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Genomic context

See Hebp2 in Genome Data Viewer
Location:
10 A3; 10 7.76 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (18415871..18421824, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (18540123..18546076, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53616 Neighboring gene NHS like 1 Neighboring gene STARR-seq mESC enhancer starr_25897 Neighboring gene family with sequence similarity 54, member A pseudogene Neighboring gene STARR-seq mESC enhancer starr_25901 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:18228522-18228723 Neighboring gene STARR-seq mESC enhancer starr_25912 Neighboring gene ARFGEF family member 3 Neighboring gene STARR-seq mESC enhancer starr_25915 Neighboring gene STARR-seq mESC enhancer starr_25916 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:18384699-18384900 Neighboring gene predicted gene, 32926 Neighboring gene predicted gene 4922

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables heme binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
heme-binding protein 2
Names
putative heme-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019487.3NP_062360.1  heme-binding protein 2

    See identical proteins and their annotated locations for NP_062360.1

    Status: PROVISIONAL

    Source sequence(s)
    AC153561
    Consensus CDS
    CCDS23711.1
    UniProtKB/Swiss-Prot
    Q9WU63
    Related
    ENSMUSP00000020000.6, ENSMUST00000020000.7
    Conserved Domains (1) summary
    pfam04832
    Location:36195
    SOUL; SOUL heme-binding protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    18415871..18421824 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)