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dvl1b dishevelled segment polarity protein 1b [ Danio rerio (zebrafish) ]

Gene ID: 560032, updated on 5-Aug-2018

Summary

Official Symbol
dvl1bprovided by ZNC
Official Full Name
dishevelled segment polarity protein 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-071004-1
See related
Ensembl:ENSDARG00000055552 Vega:OTTDARG00000008561
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
dvl1; dvl2l

Genomic context

See dvl1b in Genome Data Viewer
Location:
chromosome: 11
Exon count:
17
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (24360582..24428628, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (24123040..24191011, complement)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene si:ch211-15p9.2 Neighboring gene NFS1 cysteine desulfurase Neighboring gene matrix-remodelling associated 8a Neighboring gene pleckstrin homology domain containing, family G (with RhoGef domain) member 5a

Genomic regions, transcripts, and products

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
frizzled binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 
canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 
planar cell polarity pathway involved in neural tube closure IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
segment polarity protein dishevelled homolog DVL-1
Names
dishevelled, dsh homolog 1
dishevelled, dsh homolog 1b
dishevelled, dsh homolog 2, like

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044917.1NP_001038382.1  segment polarity protein dishevelled homolog DVL-1

    Status: PROVISIONAL

    Source sequence(s)
    BX001056
    Related
    ENSDARP00000156001.1, ENSDART00000189107.1
    Conserved Domains (5) summary
    smart00021
    Location:185
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:243330
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:386469
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:90241
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:473697
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    24360582..24428628 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005169297.4XP_005169354.1  segment polarity protein dishevelled homolog DVL-1 isoform X1

    Conserved Domains (5) summary
    smart00021
    Location:185
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:252339
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:421504
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:90250
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:508732
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
  2. XM_005169299.4XP_005169356.1  segment polarity protein dishevelled homolog DVL-1 isoform X3

    See identical proteins and their annotated locations for XP_005169356.1

    Conserved Domains (4) summary
    cd00992
    Location:152239
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:321404
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:47150
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:408632
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
  3. XM_005169298.4XP_005169355.1  segment polarity protein dishevelled homolog DVL-1 isoform X2

    UniProtKB/TrEMBL
    F1QNA4
    Related
    ENSDARP00000094527.4, OTTDARP00000008455, ENSDART00000103752.5
    Conserved Domains (5) summary
    smart00021
    Location:185
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:252339
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:395478
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:90250
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:482706
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
  4. XM_005169301.4XP_005169358.1  segment polarity protein dishevelled homolog DVL-1 isoform X4

    Conserved Domains (4) summary
    smart00021
    Location:185
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:252339
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:421504
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:90250
    Dishevelled; Dishevelled specific domain
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