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SLC25A40 solute carrier family 25 member 40 [ Homo sapiens (human) ]

Gene ID: 55972, updated on 2-Oct-2018

Summary

Official Symbol
SLC25A40provided by HGNC
Official Full Name
solute carrier family 25 member 40provided by HGNC
Primary source
HGNC:HGNC:29680
See related
Ensembl:ENSG00000075303 MIM:610821; Vega:OTTHUMG00000131033
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MCFP
Summary
SLC25A40 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008]
Expression
Ubiquitous expression in lymph node (RPKM 7.5), appendix (RPKM 7.3) and 25 other tissues See more
Orthologs

Genomic context

See SLC25A40 in Genome Data Viewer
Location:
7q21.12
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 7 NC_000007.14 (87834499..87876377, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (87462885..87505692, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein A1 pseudogene 9 Neighboring gene ATP binding cassette subfamily B member 1 Neighboring gene RUN domain containing 3B Neighboring gene origin of replication in promoter of DBF4 Neighboring gene DBF4 zinc finger Neighboring gene ADAM metallopeptidase domain 22 Neighboring gene uncharacterized LOC105375386 Neighboring gene uncharacterized LOC102723885 Neighboring gene sorcin

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
solute carrier family 25 member 40
Names
mitochondrial carrier family protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018843.3NP_061331.2  solute carrier family 25 member 40

    See identical proteins and their annotated locations for NP_061331.2

    Status: VALIDATED

    Source sequence(s)
    AC003083, AI037919, BX362003
    Consensus CDS
    CCDS5610.1
    UniProtKB/Swiss-Prot
    Q8TBP6
    Related
    ENSP00000344831.5, OTTHUMP00000161660, ENST00000341119.9, OTTHUMT00000253677
    Conserved Domains (1) summary
    pfam00153
    Location:12136
    Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p12 Primary Assembly

    Range
    87834499..87876377 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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