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Sertad1 SERTA domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 55942, updated on 12-May-2024

Summary

Official Symbol
Sertad1provided by MGI
Official Full Name
SERTA domain containing 1provided by MGI
Primary source
MGI:MGI:1913438
See related
Ensembl:ENSMUSG00000008384 AllianceGenome:MGI:1913438
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sei1; Sei-1; TRIP-Br1; 1110032C13Rik
Summary
Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in 1st branchial arch; genitourinary system; heart; and limb. Orthologous to human SERTAD1 (SERTA domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in small intestine adult (RPKM 40.2), colon adult (RPKM 32.4) and 26 other tissues See more
Orthologs
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Genomic context

See Sertad1 in Genome Data Viewer
Location:
7 A3; 7 15.91 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (27186378..27189741)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (27486953..27490316)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1336 Neighboring gene SERTA domain containing 3 Neighboring gene predicted gene, 38972 Neighboring gene STARR-positive B cell enhancer ABC_E107 Neighboring gene predicted gene 15541 Neighboring gene periaxin Neighboring gene STARR-positive B cell enhancer ABC_E4910 Neighboring gene homeodomain interacting protein kinase 4

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transcription regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in sarcoplasm IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
SERTA domain-containing protein 1
Names
CDK4-binding protein p34SEI1
PHD zinc finger- and bromodomain-interacting protein 1
p34SEI-1
transcriptional regulator interacting with the PHD-bromodomain 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418519.1NP_001405448.1  SERTA domain-containing protein 1

    Status: VALIDATED

    Source sequence(s)
    AC158304
    UniProtKB/Swiss-Prot
    Q925E6, Q9D888, Q9JL10
  2. NM_018820.5NP_061290.1  SERTA domain-containing protein 1

    See identical proteins and their annotated locations for NP_061290.1

    Status: VALIDATED

    Source sequence(s)
    AC158304
    Consensus CDS
    CCDS21022.1
    UniProtKB/Swiss-Prot
    Q925E6, Q9D888, Q9JL10
    Related
    ENSMUSP00000008528.8, ENSMUST00000008528.8
    Conserved Domains (1) summary
    pfam06031
    Location:4579
    SERTA; SERTA motif

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    27186378..27189741
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)