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LANCL2 LanC like 2 [ Homo sapiens (human) ]

Gene ID: 55915, updated on 4-Nov-2018

Summary

Official Symbol
LANCL2provided by HGNC
Official Full Name
LanC like 2provided by HGNC
Primary source
HGNC:HGNC:6509
See related
Ensembl:ENSG00000132434 MIM:612919; Vega:OTTHUMG00000023779
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TASP; GPR69B
Expression
Ubiquitous expression in brain (RPKM 16.9), testis (RPKM 9.1) and 24 other tissues See more
Orthologs

Genomic context

See LANCL2 in Genome Data Viewer
Location:
7p11.2
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 7 NC_000007.14 (55365448..55433742)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (55433141..55501435)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene calmodulin 1 pseudogene 2 Neighboring gene RNA exonuclease 1 homolog Neighboring gene VOPP1, WBP1/VOPP1 family member Neighboring gene uncharacterized LOC107986798 Neighboring gene uncharacterized LOC105375287

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

HIV-1 interactions

Replication interactions

Interaction Pubs
HIV-1 infection (VSV-G pseudotyped) of CEMT4 T cells downregulates plasma membrane expression of LANCL2 PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC87139

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding NAS
Non-traceable Author Statement
more info
PubMed 
GTP binding NAS
Non-traceable Author Statement
more info
PubMed 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
phosphatidylinositol-3-phosphate binding IDA
Inferred from Direct Assay
more info
PubMed 
phosphatidylinositol-4-phosphate binding IDA
Inferred from Direct Assay
more info
PubMed 
phosphatidylinositol-5-phosphate binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
cortical actin cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
nucleus HDA PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
lanC-like protein 2
Names
G protein-coupled receptor 69B
LanC (bacterial lantibiotic synthetase component C)-like 2
LanC lantibiotic synthetase component C-like 2
testis-specific adriamycin sensitivity protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018697.3NP_061167.1  lanC-like protein 2

    See identical proteins and their annotated locations for NP_061167.1

    Status: VALIDATED

    Source sequence(s)
    AA994905, AJ278245, AK095857, BC004887, BC070049, BF590020, BI869599
    Consensus CDS
    CCDS5517.1
    UniProtKB/Swiss-Prot
    Q9NS86
    UniProtKB/TrEMBL
    B3KTN5
    Related
    ENSP00000254770.2, OTTHUMP00000159664, ENST00000254770.2, OTTHUMT00000251459
    Conserved Domains (1) summary
    cd04794
    Location:103440
    euk_LANCL; Eukaryotic Lanthionine synthetase C-like protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p12 Primary Assembly

    Range
    55365448..55433742
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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