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adad2 adenosine deaminase domain containing 2 [ Danio rerio (zebrafish) ]

Gene ID: 558824, updated on 4-Jan-2025

Summary

Official Symbol
adad2provided by ZNC
Official Full Name
adenosine deaminase domain containing 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-130530-788
See related
Ensembl:ENSDARG00000105626 AllianceGenome:ZFIN:ZDB-GENE-130530-788
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable double-stranded RNA adenosine deaminase activity; double-stranded RNA binding activity; and tRNA-specific adenosine deaminase activity. Predicted to be involved in RNA processing and adenosine to inosine editing. Predicted to be active in cytoplasm and nucleolus. Orthologous to human ADAD2 (adenosine deaminase domain containing 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See adad2 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (24862470..24875434, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (24591313..24604347, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101885004 Neighboring gene family with sequence similarity 113 Neighboring gene citrate synthase lysine methyltransferase Neighboring gene kelch repeat-containing protein Neighboring gene MAP/microtubule affinity-regulating kinase 2b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables adenosine deaminase activity IEA
Inferred from Electronic Annotation
more info
 
enables double-stranded RNA adenosine deaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables double-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables tRNA-specific adenosine deaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in RNA processing IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within RNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in adenosine to inosine editing IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
adenosine deaminase domain-containing protein 2
Names
zmp:0000000785

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    24862470..24875434 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_682091.9XP_687183.1  adenosine deaminase domain-containing protein 2

    UniProtKB/TrEMBL
    A0A1D5NSL4, A0A8N7TDG9
    Related
    ENSDARP00000142831.1, ENSDART00000173920.2
    Conserved Domains (1) summary
    pfam02137
    Location:198509
    A_deamin; Adenosine-deaminase (editase) domain