extl2 exostosin-like glycosyltransferase 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: extl2provided by ZNC
Official Full Name: exostosin-like glycosyltransferase 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-060929-1122
See related: Ensembl:ENSDARG00000063191 AllianceGenome:ZFIN:ZDB-GENE-060929-1122
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc37e06; wu:fc37e06; zgc:153688; si:dkey-60b12.3
Summary: Predicted to enable glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Predicted to be involved in carbohydrate derivative metabolic process. Predicted to act upstream of or within protein glycosylation. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human EXTL2 (exostosin like glycosyltransferase 2). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2025_04	current	GRCz12tu (GCF_049306965.1)	2	NC_133177.1 (7403084..7450192, complement)
RS_2024_08	previous assembly	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (7123255..7131696, complement)

Chromosome 2 - NC_133177.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fc37e06.x1 (e-PCR)
- UniSTS:188063

fk20b02.y1 (e-PCR)
- UniSTS:200629

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables alpha-1,4-N-acetylgalactosaminyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in N-acetylglucosamine metabolic process	IEA Inferred from Electronic Annotation more info
involved_in UDP-N-acetylgalactosamine metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: exostosin-like 2

Names: exotoses (multiple)-like 2

NP_001070029.1

EC 2.4.1.223

XP_073774102.1

EC 2.4.1.223

XP_073774107.1

EC 2.4.1.223

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.