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adarb2 adenosine deaminase RNA specific B2 (inactive) [ Danio rerio (zebrafish) ]

Gene ID: 558149, updated on 9-Sep-2025
Official Symbol
adarb2provided by ZNC
Official Full Name
adenosine deaminase RNA specific B2 (inactive)provided by ZNC
Primary source
ZFIN:ZDB-GENE-060503-160
See related
Ensembl:ENSDARG00000071823 AllianceGenome:ZFIN:ZDB-GENE-060503-160
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-255g15.1
Summary
Predicted to enable double-stranded RNA adenosine deaminase activity; double-stranded RNA binding activity; and tRNA-specific adenosine deaminase activity. Predicted to be involved in RNA processing and adenosine to inosine editing. Predicted to be active in cytoplasm and nucleolus. Is expressed in brain and spinal cord. Orthologous to human ADARB2 (adenosine deaminase RNA specific B2 (inactive)). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
human mouse all
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See adarb2 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 24 NC_133199.1 (3724269..4322142, complement)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 24 NC_007135.7 (3529195..3867544, complement)

Chromosome 24 - NC_133199.1Genomic Context describing neighboring genes Neighboring gene NCK adaptor protein 1b Neighboring gene uncharacterized LOC141380804 Neighboring gene WD repeat domain 37 Neighboring gene uncharacterized LOC137489203 Neighboring gene uncharacterized LOC141380806 Neighboring gene class II cytokine, IFN-u Neighboring gene uncharacterized LOC141380808 Neighboring gene phosphofructokinase, platelet a Neighboring gene Kruppel like factor 6a Neighboring gene cyclin Y

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish. Niescierowicz K, et al. Nat Commun, 2022 Sep 20. PMID 36127363, Free PMC Article
  2. Fmrp Interacts with Adar and Regulates RNA Editing, Synaptic Density and Locomotor Activity in Zebrafish. Shamay-Ramot A, et al. PLoS Genet, 2015 Dec. PMID 26637167, Free PMC Article
  3. Exposure to elevated glucocorticoid during development primes altered transcriptional responses to acute stress in adulthood. Choi MK, et al. iScience, 2024 Jul 19. PMID 38989456, Free PMC Article
  4. Lef1-dependent hypothalamic neurogenesis inhibits anxiety. Xie Y, et al. PLoS Biol, 2017 Aug. PMID 28837622, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables adenosine deaminase activity IEA
Inferred from Electronic Annotation
more info
  
enables double-stranded RNA adenosine deaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables double-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables tRNA-specific adenosine deaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in RNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within RNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in adenosine to inosine editing IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
Preferred Names
double-stranded RNA-specific editase B2
Names
adenosine deaminase, RNA-specific, B2 (RED2 homolog rat)
adenosine deaminase, RNA-specific, B2 (non-functional)

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RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133199.1 Reference GRCz12tu Primary Assembly

    Range
    3724269..4322142 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_073941371.1 → XP_073797472.1  double-stranded RNA-specific editase B2 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AVV9

  2. XM_073941369.1 → XP_073797470.1  double-stranded RNA-specific editase B2 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AVV9

  3. XM_073941375.1 → XP_073797476.1  double-stranded RNA-specific editase B2 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AVV9

  4. XM_073941373.1 → XP_073797474.1  double-stranded RNA-specific editase B2 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AVV9

  5. XM_073941370.1 → XP_073797471.1  double-stranded RNA-specific editase B2 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AVV9

  6. XM_073941374.1 → XP_073797475.1  double-stranded RNA-specific editase B2 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AVV9

  7. XM_073941372.1 → XP_073797473.1  double-stranded RNA-specific editase B2 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AVV9

  8. XM_681334.10 → XP_686426.6  double-stranded RNA-specific editase B2 isoform X1

    UniProtKB/TrEMBL
    A0A8N7T6M9

  9. XM_068217139.2 → XP_068073240.2  double-stranded RNA-specific editase B2 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AVV9

RNA

  1. XR_012399654.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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