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PRR11 proline rich 11 [ Homo sapiens (human) ]

Gene ID: 55771, updated on 2-Aug-2021

Summary

Official Symbol
PRR11provided by HGNC
Official Full Name
proline rich 11provided by HGNC
Primary source
HGNC:HGNC:25619
See related
Ensembl:ENSG00000068489 MIM:615920
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in bone marrow (RPKM 3.3), lymph node (RPKM 2.7) and 20 other tissues See more
Orthologs
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Genomic context

See PRR11 in Genome Data Viewer
Location:
17q22
Exon count:
11
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (59155355..59206709)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (57233107..57284070)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene spindle and kinetochore associated complex subunit 2 Neighboring gene microRNA 454 Neighboring gene microRNA 301a Neighboring gene speedy/RINGO cell cycle regulator family member E22, pseudogene Neighboring gene SMG8 nonsense mediated mRNA decay factor Neighboring gene glycerophosphodiester phosphodiesterase domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ11029

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in regulation of cell cycle IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
proline-rich protein 11
Names
transcription repressor of MHCII

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018304.4NP_060774.2  proline-rich protein 11

    See identical proteins and their annotated locations for NP_060774.2

    Status: VALIDATED

    Source sequence(s)
    AC099850, AK225377, AW957315, DB106349
    Consensus CDS
    CCDS11614.1
    UniProtKB/Swiss-Prot
    Q96HE9
    UniProtKB/TrEMBL
    D2SNZ4
    Related
    ENSP00000262293.5, ENST00000262293.9

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    59155355..59206709
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024450828.1XP_024306596.1  proline-rich protein 11 isoform X1

    Related
    ENSP00000463733.1, ENST00000580177.5
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