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IPO9 importin 9 [ Homo sapiens (human) ]

Gene ID: 55705, updated on 9-Feb-2020

Summary

Official Symbol
IPO9provided by HGNC
Official Full Name
importin 9provided by HGNC
Primary source
HGNC:HGNC:19425
See related
Ensembl:ENSG00000198700
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Imp9
Expression
Ubiquitous expression in brain (RPKM 7.6), thyroid (RPKM 6.7) and 25 other tissues See more
Orthologs

Genomic context

See IPO9 in Genome Data Viewer
Location:
1q32.1
Exon count:
24
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (201829157..201884291)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (201798288..201853422)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene neuron navigator 1 Neighboring gene IPO9 antisense RNA 1 Neighboring gene RNA, U6 small nuclear 501, pseudogene Neighboring gene Sharpr-MPRA regulatory region 13839 Neighboring gene microRNA 1231 Neighboring gene Sharpr-MPRA regulatory region 11581 Neighboring gene Sharpr-MPRA regulatory region 2190 Neighboring gene microRNA 6739 Neighboring gene shisa family member 4 Neighboring gene leiomodin 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Vpu vpu HIV-1 Vpu is identified to have a physical interaction with importin 9 (IPO9) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10402, DKFZp761M1547

Gene Ontology Provided by GOA

Function Evidence Code Pubs
Ran GTPase binding IEA
Inferred from Electronic Annotation
more info
 
histone binding ISS
Inferred from Sequence or Structural Similarity
more info
 
nuclear import signal receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
protein import into nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein import into nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane HDA PubMed 
nuclear envelope IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
importin-9
Names
ran-binding protein 9
ranBP9

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018085.5NP_060555.2  importin-9

    See identical proteins and their annotated locations for NP_060555.2

    Status: VALIDATED

    Source sequence(s)
    AF410465, AL513217, AL645504, DA861528, DB232332
    Consensus CDS
    CCDS1415.1
    UniProtKB/Swiss-Prot
    Q96P70
    Related
    ENSP00000354742.4, ENST00000361565.9
    Conserved Domains (1) summary
    COG5657
    Location:34812
    CSE1; CAS/CSE protein involved in chromosome segregation [Cell division and chromosome partitioning]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    201829157..201884291
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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