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ZNF416 zinc finger protein 416 [ Homo sapiens (human) ]

Gene ID: 55659, updated on 23-Nov-2021

Summary

Official Symbol
ZNF416provided by HGNC
Official Full Name
zinc finger protein 416provided by HGNC
Primary source
HGNC:HGNC:20645
See related
Ensembl:ENSG00000083817
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in testis (RPKM 2.5), thyroid (RPKM 1.9) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF416 in Genome Data Viewer
Location:
19q13.43
Exon count:
5
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (57571015..57578911, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (58082934..58090279, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 549 Neighboring gene zinc finger protein 550 Neighboring gene zinc finger protein interacting with K protein 1 Neighboring gene zinc finger protein 530

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ20557

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001353405.2NP_001340334.1  zinc finger protein 416 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC003682
    Conserved Domains (4) summary
    COG5048
    Location:253434
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:418501
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:200220
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:212237
    zf-H2C2_2; Zinc-finger double domain
  2. NM_017879.3NP_060349.1  zinc finger protein 416 isoform 1

    See identical proteins and their annotated locations for NP_060349.1

    Status: VALIDATED

    Source sequence(s)
    AC003682
    Consensus CDS
    CCDS12954.1
    UniProtKB/Swiss-Prot
    Q9BWM5
    Related
    ENSP00000196489.2, ENST00000196489.4
    Conserved Domains (4) summary
    COG5048
    Location:77506
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:490573
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:272292
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:2867
    KRAB; KRAB box

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    57571015..57578911 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024451594.1XP_024307362.1  zinc finger protein 416 isoform X1

    Conserved Domains (4) summary
    COG5048
    Location:57486
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:470553
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:252272
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:847
    KRAB; KRAB box
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