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OSGEP O-sialoglycoprotein endopeptidase [ Homo sapiens (human) ]

Gene ID: 55644, updated on 7-Jun-2020

Summary

Official Symbol
OSGEPprovided by HGNC
Official Full Name
O-sialoglycoprotein endopeptidaseprovided by HGNC
Primary source
HGNC:HGNC:18028
See related
Ensembl:ENSG00000092094 MIM:610107
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KAE1; TCS3; GCPL1; GAMOS3; OSGEP1; PRSMG1
Expression
Ubiquitous expression in spleen (RPKM 14.4), lymph node (RPKM 12.5) and 25 other tissues See more
Orthologs

Genomic context

See OSGEP in Genome Data Viewer
Location:
14q11.2
Exon count:
11
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (20446401..20454812, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (20915207..20923267, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene kelch like family member 33 Neighboring gene solute carrier family 12 member 3 pseudogene Neighboring gene OSGEP/APEX1 bi-directional promoter region Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 1 Neighboring gene phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 Neighboring gene purine nucleoside phosphorylase

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20411

Gene Ontology Provided by GOA

Function Evidence Code Pubs
N(6)-L-threonylcarbamoyladenine synthase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
tRNA threonylcarbamoyladenosine modification IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
EKC/KEOPS complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
EKC/KEOPS complex IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nuclear speck IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
probable tRNA N6-adenosine threonylcarbamoyltransferase
Names
N6-L-threonylcarbamoyladenine synthase
hOSGEP
probable O-sialoglycoprotein endopeptidase
probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP
t(6)A synthase
t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP
tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP
NP_060277.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017807.4NP_060277.1  probable tRNA N6-adenosine threonylcarbamoyltransferase

    See identical proteins and their annotated locations for NP_060277.1

    Status: VALIDATED

    Source sequence(s)
    AL355075, CD365329
    Consensus CDS
    CCDS9549.1
    UniProtKB/Swiss-Prot
    Q9NPF4
    Related
    ENSP00000206542.4, ENST00000206542.9
    Conserved Domains (1) summary
    PTZ00340
    Location:4335
    PTZ00340; O-sialoglycoprotein endopeptidase-like protein; Provisional

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    20446401..20454812 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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