phka2 phosphorylase kinase, alpha 2 (liver) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: phka2provided by ZNC
Official Full Name: phosphorylase kinase, alpha 2 (liver)provided by ZNC
Primary source: ZFIN:ZDB-GENE-130422-1
See related: Ensembl:ENSDARG00000030687 AllianceGenome:ZFIN:ZDB-GENE-130422-1
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable calmodulin binding activity. Predicted to be involved in glycogen metabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in cytoplasm and plasma membrane. Predicted to be part of phosphorylase kinase complex. Used to study visceral heterotaxy. Human ortholog(s) of this gene implicated in glycogen storage disease and glycogen storage disease IXa. Orthologous to human PHKA2 (phosphorylase kinase regulatory subunit alpha 2). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
RS_2025_04	current	GRCz12tu (GCF_049306965.1)	11	NC_133186.1 (36159354..36208472, complement)
RS_2024_08	previous assembly	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (33870357..33919568, complement)

Chromosome 11 - NC_133186.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables calmodulin binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within glycogen metabolic process	IEA Inferred from Electronic Annotation more info
involved_in glycogen metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of phosphorylase kinase complex	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

Preferred Names: phosphorylase b kinase regulatory subunit alpha, liver isoform

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The following sections contain reference sequences that belong to a specific genome build. Explain