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pdk1 pyruvate dehydrogenase kinase, isozyme 1 [ Danio rerio (zebrafish) ]

Gene ID: 555840, updated on 13-Jun-2020

Summary

Official Symbol
pdk1provided by ZNC
Official Full Name
pyruvate dehydrogenase kinase, isozyme 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-091204-402
See related
Ensembl:ENSDARG00000013128
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:zfos-979f1.3
Orthologs

Genomic context

See pdk1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
12
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (3131365..3149983, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (3125345..3144028, complement)
103 previous assembly Zv9 (GCF_000002035.4) 9 NC_007120.5 (3131463..3148601, complement)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene si:ch211-173m16.2 Neighboring gene protein phosphatase 1 regulatory subunit 9A-like A Neighboring gene finTRIM family, member 52, pseudogene Neighboring gene dynein, cytoplasmic 1, intermediate chain 2a

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
glucose homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of pyruvate dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial; pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial
XP_683576.2

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    3131365..3149983 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_678484.6XP_683576.2  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial

    UniProtKB/TrEMBL
    E7F3U3
    Related
    ENSDARP00000022009.6, ENSDART00000020861.7
    Conserved Domains (3) summary
    smart00387
    Location:239359
    HATPase_c; Histidine kinase-like ATPases
    COG0642
    Location:229358
    BaeS; Signal transduction histidine kinase [Signal transduction mechanisms]
    pfam10436
    Location:25189
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

RNA

  1. XR_002459480.1 RNA Sequence

  2. XR_002459479.1 RNA Sequence

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