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map3k5 mitogen-activated protein kinase kinase kinase 5 [ Danio rerio (zebrafish) ]

Gene ID: 555703, updated on 17-Nov-2020

Summary

Official Symbol
map3k5provided by ZNC
Official Full Name
mitogen-activated protein kinase kinase kinase 5provided by ZNC
Primary source
ZFIN:ZDB-GENE-030827-3
See related
Ensembl:ENSDARG00000005416
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
As; Ask1
Orthologs

Genomic context

See map3k5 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
30
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (3005539..3087115, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (2993688..3073675, complement)
103 previous assembly Zv9 (GCF_000002035.4) 20 NC_007131.5 (3039015..3120410, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene adenosylmethionine decarboxylase 1 Neighboring gene peptidylprolyl isomerase (cyclophilin)-like 4 Neighboring gene transfer RNA serine (anticodon UGA) Neighboring gene transfer RNA serine (anticodon CGA)

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
MAP kinase kinase kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
MAP kinase kinase kinase activity IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
activation of MAPKK activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular response to stress IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
mitogen-activated protein kinase kinase kinase 5
NP_001155222.1
XP_021324097.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001161750.1NP_001155222.1  mitogen-activated protein kinase kinase kinase 5

    Status: PROVISIONAL

    Source sequence(s)
    BX248523
    UniProtKB/TrEMBL
    E7F2L3
    Related
    ENSDARP00000046640.6, ENSDART00000046641.9
    Conserved Domains (3) summary
    smart00220
    Location:674927
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06624
    Location:660927
    STKc_ASK; Catalytic domain of the Serine/Threonine Kinase, Apoptosis signal-regulating kinase
    pfam13281
    Location:152531
    DUF4071; Domain of unknown function (DUF4071)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    3005539..3087115 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021468422.1XP_021324097.1  mitogen-activated protein kinase kinase kinase 5 isoform X1

    Related
    ENSDARP00000126631.1, ENSDART00000152495.3
    Conserved Domains (2) summary
    cd06624
    Location:652919
    STKc_ASK; Catalytic domain of the Serine/Threonine Kinase, Apoptosis signal-regulating kinase
    pfam13281
    Location:152523
    DUF4071; Domain of unknown function (DUF4071)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395060.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    106778..181709 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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