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FEM1A fem-1 homolog A [ Homo sapiens (human) ]

Gene ID: 55527, updated on 12-Oct-2019

Summary

Official Symbol
FEM1Aprovided by HGNC
Official Full Name
fem-1 homolog Aprovided by HGNC
Primary source
HGNC:HGNC:16934
See related
Ensembl:ENSG00000141965 MIM:613538
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EPRAP
Orthologs

Genomic context

See FEM1A in Genome Data Viewer
Location:
19p13.3
Exon count:
1
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (4791734..4801273)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (4791728..4795571)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 15136 Neighboring gene MIR7-3 host gene Neighboring gene microRNA 7-3 Neighboring gene toll like receptor adaptor molecule 1 Neighboring gene perilipin 3 Neighboring gene arrestin domain containing 5

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp762M136

Gene Ontology Provided by GOA

Function Evidence Code Pubs
EP4 subtype prostaglandin E2 receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
negative regulation of inflammatory response IDA
Inferred from Direct Assay
more info
PubMed 
post-translational protein modification TAS
Traceable Author Statement
more info
 
protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
regulation of ubiquitin-protein transferase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cytosol TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
protein fem-1 homolog A
Names
FEM1-alpha
prostaglandin E receptor 4-associated protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018708.3NP_061178.1  protein fem-1 homolog A

    See identical proteins and their annotated locations for NP_061178.1

    Status: VALIDATED

    Source sequence(s)
    AC005523
    Consensus CDS
    CCDS12135.1
    UniProtKB/Swiss-Prot
    Q9BSK4
    Related
    ENSP00000269856.3, ENST00000269856.5
    Conserved Domains (6) summary
    smart00248
    Location:4370
    ANK; ankyrin repeats
    cd00204
    Location:82203
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:87179
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:183235
    Ank_4; Ankyrin repeats (many copies)
    pfam13857
    Location:567620
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:82113
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    4791734..4801273
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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