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inhbab inhibin subunit beta Ab [ Danio rerio (zebrafish) ]

Gene ID: 553816, updated on 9-Sep-2025
Official Symbol
inhbabprovided by ZNC
Official Full Name
inhibin subunit beta Abprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050525-2
See related
Ensembl:ENSDARG00000024759 AllianceGenome:ZFIN:ZDB-GENE-050525-2
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
inhbal; zgc:158348
Summary
Predicted to enable cytokine activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in ovarian follicle. Orthologous to human INHBA (inhibin subunit beta A). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
human mouse all
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See inhbab in Genome Data Viewer
Location:
chromosome: 2
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 2 NC_133177.1 (24710825..24728044)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 2 NC_007113.7 (21486529..21503748)

Chromosome 2 - NC_133177.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC141378048 Neighboring gene AFG3-like AAA ATPase 2 Neighboring gene uncharacterized LOC141378049 Neighboring gene uncharacterized LOC141378047 Neighboring gene uncharacterized LOC141378046

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. Luteinizing hormone receptor (lhcgr) as a marker gene for characterizing estrogenic endocrine-disrupting chemicals in zebrafish ovarian follicle cells. Liu KC, et al. Gen Comp Endocrinol, 2013 Oct 1. PMID 23851042
  2. Involvement of cyclic adenosine 3',5'-monophosphate in the differential regulation of activin betaA and betaB expression by gonadotropin in the zebrafish ovarian follicle cells. Wang Y, et al. Endocrinology, 2003 Feb. PMID 12538609
  3. Intrafollicular paracrine communication in the zebrafish ovary: the state of the art of an emerging model for the study of vertebrate folliculogenesis. Ge W. Mol Cell Endocrinol, 2005 Jun 15. PMID 15921848
  4. Human chorionic gonadotropin (hCG) induces MAPK3/1 phosphorylation in the zebrafish ovarian follicle cells independent of EGF/EGFR pathway. Chung CK, et al. Gen Comp Endocrinol, 2013 Jul 1. PMID 23644153
  5. Stable multilineage xenogeneic replacement of definitive hematopoiesis in adult zebrafish. Hess I, et al. Sci Rep, 2016 Jan 18. PMID 26777855, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The present study demonstrated that EGF controlled expression of three activin subunits (inhbaa, inhbab and inhbb) in the follicle cells via diverse signaling pathways.
    Title: Epidermal growth factor differentially regulates activin subunits in the zebrafish ovarian follicle cells via diverse signaling pathways.
Submit: New GeneRIF Correction

Homology

Clone Names

  • MGC158348

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cytokine activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
  
enables hormone activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in animal organ development IEA
Inferred from Electronic Annotation
more info
  
involved_in cell development IEA
Inferred from Electronic Annotation
more info
  
involved_in cell surface receptor protein serine/threonine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
involved_in system development IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  
Preferred Names
inhibin subunit beta Ab
Names
activin beta A2
activin betaA
inhibin, beta A, like
inhibin, beta Ab

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001018156.1 → NP_001018166.1  inhibin subunit beta Ab precursor

    See identical proteins and their annotated locations for NP_001018166.1

    Status: PROVISIONAL

    Source sequence(s)
    BC129208
    UniProtKB/TrEMBL
    A1L1T8
    Related
    ENSDARP00000047467.6, ENSDART00000047468.7
    Conserved Domains (2) summary
    pfam00019
    Location:298 → 404
    TGF_beta; Transforming growth factor beta like domain
    pfam00688
    Location:64 → 272
    TGFb_propeptide; TGF-beta propeptide

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133177.1 Reference GRCz12tu Primary Assembly

    Range
    24710825..24728044
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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