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gba3 glucosidase, beta, acid 3 (gene/pseudogene) [ Danio rerio (zebrafish) ]

Gene ID: 553722, updated on 4-Jan-2025

Summary

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Official Symbol
gba3provided by ZNC
Official Full Name
glucosidase, beta, acid 3 (gene/pseudogene)provided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-351
See related
Ensembl:ENSDARG00000031150 AllianceGenome:ZFIN:ZDB-GENE-050522-351
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:6912508; zgc:112375
Summary
Predicted to enable beta-galactosidase activity and glycosylceramidase activity. Predicted to be involved in glycosylceramide catabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be active in cytosol. Orthologous to human GBA3 (glucosylceramidase beta 3 (gene/pseudogene)). [provided by Alliance of Genome Resources, Jan 2025]
Annotation information
Annotation category: partial on reference assembly
Orthologs
all
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Genomic context

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See gba3 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (70338270..70344449)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (69887973..69894167)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene potassium voltage-gated channel interacting protein 4a Neighboring gene adhesion G protein-coupled receptor A3-like Neighboring gene adhesion G protein-coupled receptor A3 Neighboring gene peroxisome proliferator-activated receptor gamma, coactivator 1 alpha Neighboring gene uncharacterized LOC137496242

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC112375

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables beta-galactosidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables beta-glucosidase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosylceramidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in glycosylceramide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cytosolic beta-glucosidase
NP_001018529.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001020693.1 → NP_001018529.1  cytosolic beta-glucosidase

    Status: PROVISIONAL

    Source sequence(s)
    BC095794
    UniProtKB/TrEMBL
    Q502A1
    Related
    ENSDARP00000065233.6, ENSDART00000065234.7
    Conserved Domains (1) summary
    cl23725
    Location:9 → 466
    Glyco_hydro_1; Glycosyl hydrolase family 1

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    70338270..70344449
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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