Format

Send to:

Choose Destination

COPRS coordinator of PRMT5 and differentiation stimulator [ Homo sapiens (human) ]

Gene ID: 55352, updated on 1-Jun-2020

Summary

Official Symbol
COPRSprovided by HGNC
Official Full Name
coordinator of PRMT5 and differentiation stimulatorprovided by HGNC
Primary source
HGNC:HGNC:28848
See related
Ensembl:ENSG00000172301
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TTP1; COPR5; C17orf79; HSA272196
Expression
Broad expression in testis (RPKM 66.1), brain (RPKM 19.5) and 22 other tissues See more
Orthologs

Genomic context

See COPRS in Genome Data Viewer
Location:
17q11.2
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (31851871..31859244, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (30178884..30186326, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene GPR160 pseudogene 2 Neighboring gene Sharpr-MPRA regulatory region 4911 Neighboring gene UTP6 small subunit processome component Neighboring gene SUZ12 polycomb repressive complex 2 subunit Neighboring gene RNA, 5S ribosomal pseudogene 437

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ21119

Gene Ontology Provided by GOA

Function Evidence Code Pubs
histone binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histone binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
histone H4-R3 methylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histone H4-R3 methylation IDA
Inferred from Direct Assay
more info
PubMed 
muscle organ development ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleoplasm TAS
Traceable Author Statement
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
coordinator of PRMT5 and differentiation stimulator
Names
cooperator of PRMT5
coordinator of PRMT5, differentiation stimulator

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001330176.2NP_001317105.1  coordinator of PRMT5 and differentiation stimulator isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC004253, BE899028, BM784600, BQ671018, CD557513
    Consensus CDS
    CCDS82100.1
    UniProtKB/TrEMBL
    H9KV77
    Related
    ENSP00000367901.2, ENST00000378634.6
    Conserved Domains (1) summary
    pfam15340
    Location:22172
    COPR5; Cooperator of PRMT5 family
  2. NM_018405.4NP_060875.2  coordinator of PRMT5 and differentiation stimulator isoform 1

    See identical proteins and their annotated locations for NP_060875.2

    Status: VALIDATED

    Source sequence(s)
    AF407672, BQ671018, DB472863
    Consensus CDS
    CCDS11268.1
    UniProtKB/Swiss-Prot
    Q9NQ92
    Related
    ENSP00000304327.6, ENST00000302362.11
    Conserved Domains (1) summary
    pfam15340
    Location:34184
    COPR5; Cooperator of PRMT5 family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    31851871..31859244 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center