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TCP11L1 t-complex 11 like 1 [ Homo sapiens (human) ]

Gene ID: 55346, updated on 17-Jun-2024

Summary

Official Symbol
TCP11L1provided by HGNC
Official Full Name
t-complex 11 like 1provided by HGNC
Primary source
HGNC:HGNC:25655
See related
Ensembl:ENSG00000176148 AllianceGenome:HGNC:25655
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
dJ85M6.3
Summary
Predicted to be involved in signal transduction. Located in microtubule. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in brain (RPKM 7.3), small intestine (RPKM 3.3) and 25 other tissues See more
Orthologs
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Genomic context

See TCP11L1 in Genome Data Viewer
Location:
11p13
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (33039572..33073563)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (33175146..33209116)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (33061118..33095109)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene glutamine and serine rich 1 Neighboring gene uncharacterized LOC105376615 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:33022947-33023448 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4569 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4570 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3229 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3230 Neighboring gene DEP domain containing 7 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:33060521-33061068 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3231 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4572 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:33071407-33071907 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr11:33082368-33083567 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:33089797-33090298 Neighboring gene long intergenic non-protein coding RNA 294 Neighboring gene phosphatidylinositol glycan anchor biosynthesis class C pseudogene 1 Neighboring gene cleavage stimulation factor subunit 3 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:33181388-33182255 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4574

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ11336, FLJ11386

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in microtubule IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
T-complex protein 11-like protein 1
Names
t-complex 11, testis-specific-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145541.1NP_001139013.1  T-complex protein 11-like protein 1

    See identical proteins and their annotated locations for NP_001139013.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC131263, AK002198, BP281502, DA340843
    Consensus CDS
    CCDS7882.1
    UniProtKB/Swiss-Prot
    D3DR01, Q8IVX4, Q9NUJ3
    UniProtKB/TrEMBL
    B3KQZ4
    Related
    ENSP00000395070.1, ENST00000432887.5
    Conserved Domains (1) summary
    pfam05794
    Location:78502
    Tcp11; T-complex protein 11
  2. NM_018393.4NP_060863.3  T-complex protein 11-like protein 1

    See identical proteins and their annotated locations for NP_060863.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC131263, AK090646, BP281502, DA088926
    Consensus CDS
    CCDS7882.1
    UniProtKB/Swiss-Prot
    D3DR01, Q8IVX4, Q9NUJ3
    UniProtKB/TrEMBL
    B3KQZ4
    Related
    ENSP00000335595.4, ENST00000334274.9
    Conserved Domains (1) summary
    pfam05794
    Location:78502
    Tcp11; T-complex protein 11

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    33039572..33073563
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011520207.3XP_011518509.1  T-complex protein 11-like protein 1 isoform X2

    See identical proteins and their annotated locations for XP_011518509.1

    UniProtKB/Swiss-Prot
    D3DR01, Q8IVX4, Q9NUJ3
    UniProtKB/TrEMBL
    B3KQZ4
    Related
    ENSP00000433067.1, ENST00000531632.6
    Conserved Domains (1) summary
    pfam05794
    Location:78502
    Tcp11; T-complex protein 11
  2. XM_017017989.3XP_016873478.1  T-complex protein 11-like protein 1 isoform X1

    UniProtKB/TrEMBL
    B3KQZ4
    Conserved Domains (1) summary
    pfam05794
    Location:78505
    Tcp11; T-complex protein 11
  3. XM_047427237.1XP_047283193.1  T-complex protein 11-like protein 1 isoform X4

  4. XM_011520205.3XP_011518507.1  T-complex protein 11-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011518507.1

    UniProtKB/TrEMBL
    B3KQZ4
    Conserved Domains (1) summary
    pfam05794
    Location:78505
    Tcp11; T-complex protein 11
  5. XM_017017990.2XP_016873479.1  T-complex protein 11-like protein 1 isoform X2

    UniProtKB/Swiss-Prot
    D3DR01, Q8IVX4, Q9NUJ3
    UniProtKB/TrEMBL
    B3KQZ4
    Conserved Domains (1) summary
    pfam05794
    Location:78502
    Tcp11; T-complex protein 11
  6. XM_011520206.3XP_011518508.1  T-complex protein 11-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011518508.1

    UniProtKB/TrEMBL
    B3KQZ4
    Conserved Domains (1) summary
    pfam05794
    Location:78505
    Tcp11; T-complex protein 11
  7. XM_011520204.3XP_011518506.1  T-complex protein 11-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011518506.1

    UniProtKB/TrEMBL
    B3KQZ4
    Conserved Domains (1) summary
    pfam05794
    Location:78505
    Tcp11; T-complex protein 11
  8. XM_047427236.1XP_047283192.1  T-complex protein 11-like protein 1 isoform X3

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    33175146..33209116
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054369299.1XP_054225274.1  T-complex protein 11-like protein 1 isoform X1

    UniProtKB/TrEMBL
    B3KQZ4
  2. XM_054369307.1XP_054225282.1  T-complex protein 11-like protein 1 isoform X4

  3. XM_054369304.1XP_054225279.1  T-complex protein 11-like protein 1 isoform X2

    UniProtKB/TrEMBL
    B3KQZ4
  4. XM_054369303.1XP_054225278.1  T-complex protein 11-like protein 1 isoform X2

    UniProtKB/TrEMBL
    B3KQZ4
  5. XM_054369300.1XP_054225275.1  T-complex protein 11-like protein 1 isoform X1

    UniProtKB/TrEMBL
    B3KQZ4
  6. XM_054369301.1XP_054225276.1  T-complex protein 11-like protein 1 isoform X1

    UniProtKB/TrEMBL
    B3KQZ4
  7. XM_054369302.1XP_054225277.1  T-complex protein 11-like protein 1 isoform X1

    UniProtKB/TrEMBL
    B3KQZ4
  8. XM_054369305.1XP_054225280.1  T-complex protein 11-like protein 1 isoform X5

    UniProtKB/TrEMBL
    B3KQZ4
  9. XM_054369306.1XP_054225281.1  T-complex protein 11-like protein 1 isoform X3