U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TMEM144 transmembrane protein 144 [ Homo sapiens (human) ]

Gene ID: 55314, updated on 22-Sep-2022

Summary

Official Symbol
TMEM144provided by HGNC
Official Full Name
transmembrane protein 144provided by HGNC
Primary source
HGNC:HGNC:25633
See related
Ensembl:ENSG00000164124 AllianceGenome:HGNC:25633
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable carbohydrate transmembrane transporter activity. Predicted to be involved in carbohydrate transmembrane transport. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in brain (RPKM 40.3), duodenum (RPKM 10.7) and 13 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See TMEM144 in Genome Data Viewer
Location:
4q32.1
Exon count:
14
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (158210486..158255416)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (161562668..161607571)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (159131638..159176568)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928007 Neighboring gene GASK1B antisense RNA 1 Neighboring gene NUDT19 pseudogene 5 Neighboring gene Sharpr-MPRA regulatory region 4077 Neighboring gene AIDA pseudogene 2 Neighboring gene Sharpr-MPRA regulatory region 15052

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ11155

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables carbohydrate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in carbohydrate transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018342.5NP_060812.2  transmembrane protein 144

    See identical proteins and their annotated locations for NP_060812.2

    Status: VALIDATED

    Source sequence(s)
    AC098679, BC054487
    Consensus CDS
    CCDS3799.1
    UniProtKB/Swiss-Prot
    Q7Z5S9, Q9NUT3
    Related
    ENSP00000296529.6, ENST00000296529.11
    Conserved Domains (1) summary
    pfam07857
    Location:9344
    TMEM144; Transmembrane family, TMEM144 of transporters

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    158210486..158255416
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005263110.3XP_005263167.1  transmembrane protein 144 isoform X1

    See identical proteins and their annotated locations for XP_005263167.1

    UniProtKB/Swiss-Prot
    Q7Z5S9, Q9NUT3
    Conserved Domains (1) summary
    pfam07857
    Location:9344
    TMEM144; Transmembrane family, TMEM144 of transporters
  2. XM_017008366.2XP_016863855.1  transmembrane protein 144 isoform X1

    UniProtKB/Swiss-Prot
    Q7Z5S9, Q9NUT3
    Conserved Domains (1) summary
    pfam07857
    Location:9344
    TMEM144; Transmembrane family, TMEM144 of transporters
  3. XM_047415908.1XP_047271864.1  transmembrane protein 144 isoform X2

    UniProtKB/TrEMBL
    D6RDI4
    Related
    ENSP00000420930.1, ENST00000511532.5

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    161562668..161607571
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)