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GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 [ Canis lupus familiaris (dog) ]

Gene ID: 553102, updated on 25-Jul-2026
Official Symbol
GUCY1B1provided by VGNC
Official Full Name
guanylate cyclase 1 soluble subunit beta 1provided by VGNC
Primary source
VGNC:VGNC:41568
See related
Ensembl:ENSCAFG00845010585 RGD:12202654
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
GUC1B3; GUCSB3; GUCY1B3
Orthologs
all
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Try the new Transcripts and proteins table
See GUCY1B1 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
15
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 15 NC_051819.1 (53972715..54019854)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 15 NC_006597.4 (53601513..53647751)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 15 NC_049236.1 (53649434..53695985)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 15 NC_049275.1 (53226121..53272692)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 15 NC_049756.1 (53335788..53382060)

Chromosome 15 - NC_051819.1Genomic Context describing neighboring genes Neighboring gene ragulator complex protein LAMTOR3-like Neighboring gene guanylate cyclase 1 soluble subunit alpha 1 Neighboring gene trifunctional enzyme subunit beta, mitochondrial-like Neighboring gene acid sensing ion channel subunit family member 5

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. NO responsiveness in pulmonary artery and airway smooth muscle: the role of cGMP regulation. Kwak YL, et al. Am J Physiol Lung Cell Mol Physiol, 2006 Jan. PMID 16113048
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanylate cyclase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cGMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to oxygen levels IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of guanylate cyclase complex, soluble IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
guanylate cyclase soluble subunit beta-1
Names
GCS-beta-1
GCS-beta-3
guanylate cyclase soluble subunit beta-3
soluble guanylate cyclase 1 beta 3
soluble guanylate cyclase small subunit
NP_001018044.1
XP_038543126.1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001018034.2 → NP_001018044.1  guanylate cyclase soluble subunit beta-1

    See identical proteins and their annotated locations for NP_001018044.1

    Status: VALIDATED

    Source sequence(s)
    DQ008576
    UniProtKB/Swiss-Prot
    Q4ZHR9
    UniProtKB/TrEMBL
    A0A8C0JQF9, A0A8I3NS20
    Related
    ENSCAFP00845014661.1, ENSCAFT00845018777.1
    Conserved Domains (3) summary
    pfam00211
    Location:412 → 605
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam07700
    Location:2 → 166
    HNOB; Haem-NO-binding
    pfam07701
    Location:207 → 406
    HNOBA; Heme NO binding associated

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051819.1 Reference ROS_Cfam_1.0

    Range
    53972715..54019854
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038687198.1 → XP_038543126.1  guanylate cyclase soluble subunit beta-1 isoform X1

    UniProtKB/TrEMBL
    A0A8I3NS20
    Conserved Domains (3) summary
    pfam00211
    Location:344 → 537
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam07700
    Location:1 → 98
    HNOB; Haem-NO-binding
    pfam07701
    Location:139 → 338
    HNOBA; Heme NO binding associated

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049275.1 Alternate UMICH_Zoey_3.1

    Range
    53226121..53272692
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049756.1 Alternate UNSW_CanFamBas_1.0

    Range
    53335788..53382060
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049236.1 Alternate UU_Cfam_GSD_1.0

    Range
    53649434..53695985
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    53601513..53647751
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4ZHR9.1 GenPept UniProtKB/Swiss-Prot:Q4ZHR9

Gene LinkOut

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Molecular Biology Databases
Research Materials