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GIMAP4 GTPase, IMAP family member 4 [ Homo sapiens (human) ]

Gene ID: 55303, updated on 21-Dec-2019

Summary

Official Symbol
GIMAP4provided by HGNC
Official Full Name
GTPase, IMAP family member 4provided by HGNC
Primary source
HGNC:HGNC:21872
See related
Ensembl:ENSG00000133574 MIM:608087
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IAN1; IAN-1; IMAP4; MSTP062
Summary
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The encoded protein of this gene may be negatively regulated by T-cell acute lymphocytic leukemia 1 (TAL1). In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]
Expression
Broad expression in lymph node (RPKM 64.9), spleen (RPKM 59.9) and 22 other tissues See more
Orthologs

Genomic context

See GIMAP4 in Genome Data Viewer
Location:
7q36.1
Exon count:
3
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (150567370..150573953)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (150264458..150271043)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene aldehyde dehydrogenase 7 family member A1 pseudogene 3 Neighboring gene endogenous retrovirus group K member 19 Env polyprotein-like Neighboring gene eukaryotic translation initiation factor 2A pseudogene 2 Neighboring gene transient receptor potential cation channel subfamily C member 6 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ11110

Gene Ontology Provided by GOA

Function Evidence Code Pubs
GTP binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
GTPase IMAP family member 4
Names
human immune associated nucleotide 1
immune-associated nucleotide-binding protein 1
immunity associated protein 4
immunity-associated nucleotide 1 protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001363532.1NP_001350461.1  GTPase IMAP family member 4 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AF117333, AK301441, DA161191
    Consensus CDS
    CCDS87564.1
    Related
    ENSP00000419545.1, ENST00000461940.5
    Conserved Domains (2) summary
    cd01852
    Location:45245
    AIG1; AvrRpt2-Induced Gene 1 (AIG1)
    cl27055
    Location:217316
    MutS_III; MutS domain III
  2. NM_018326.3NP_060796.1  GTPase IMAP family member 4 isoform 1

    See identical proteins and their annotated locations for NP_060796.1

    Status: REVIEWED

    Source sequence(s)
    AF117333, BX476689
    Consensus CDS
    CCDS5904.1
    UniProtKB/Swiss-Prot
    Q9NUV9
    UniProtKB/TrEMBL
    A0A090N7X0
    Related
    ENSP00000255945.2, ENST00000255945.4
    Conserved Domains (2) summary
    cd01852
    Location:31231
    AIG1; AvrRpt2-Induced Gene 1 (AIG1)
    cl27055
    Location:203302
    MutS_III; MutS domain III

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    150567370..150573953
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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