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DNAJC25-GNG10 DNAJC25-GNG10 readthrough [ Homo sapiens (human) ]

Gene ID: 552891, updated on 13-May-2022

Summary

Official Symbol
DNAJC25-GNG10provided by HGNC
Official Full Name
DNAJC25-GNG10 readthroughprovided by HGNC
Primary source
HGNC:HGNC:37501
See related
Ensembl:ENSG00000244115 AllianceGenome:HGNC:37501
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This gene represents naturally-occurring mRNAs that are co-transcribed products of the neighboring DNAJC25 and GNG10 genes. These transcripts include the first exon of DNAJC25 and the last two exons of GNG10, resulting in a protein that combines the N-terminus of DNAJC25 and the C-terminus of GNG10. [provided by RefSeq, Dec 2008]
Expression
Ubiquitous expression in appendix (RPKM 46.3), adrenal (RPKM 41.5) and 25 other tissues See more
Orthologs
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Genomic context

See DNAJC25-GNG10 in Genome Data Viewer
Location:
9q31.3
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (111631334..111670226)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (123802699..123841586)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (114393614..114432506)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 37 member A5, pseudogene Neighboring gene uncharacterized LOC107987116 Neighboring gene FOXA motif-containing MPRA enhancer 227 Neighboring gene Sharpr-MPRA regulatory region 12797 Neighboring gene DnaJ heat shock protein family (Hsp40) member C25 Neighboring gene Sharpr-MPRA regulatory region 3205 Neighboring gene G protein subunit gamma 10 Neighboring gene shortage in chiasmata 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

General protein information

Preferred Names
DNAJC25-GNG10 protein
Names
DNAJC25-GNG10 readthrough transcript

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_004125.4NP_004116.2  DNAJC25-GNG10 protein precursor

    See identical proteins and their annotated locations for NP_004116.2

    Status: VALIDATED

    Source sequence(s)
    AL135787, BC015391
    UniProtKB/Swiss-Prot
    Q9H1X3
    UniProtKB/TrEMBL
    A0A024R161
    Related
    ENSP00000363412.3, ENST00000374294.3
    Conserved Domains (2) summary
    cd00068
    Location:92148
    GGL; G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors
    pfam00226
    Location:49112
    DnaJ; DnaJ domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    111631334..111670226
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    123802699..123841586
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)