Format

Send to:

Choose Destination

LRRC36 leucine rich repeat containing 36 [ Homo sapiens (human) ]

Gene ID: 55282, updated on 23-Nov-2021

Summary

Official Symbol
LRRC36provided by HGNC
Official Full Name
leucine rich repeat containing 36provided by HGNC
Primary source
HGNC:HGNC:25615
See related
Ensembl:ENSG00000159708
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RORBP70; XLHSRF2
Expression
Biased expression in testis (RPKM 11.4), lung (RPKM 7.2) and 1 other tissue See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See LRRC36 in Genome Data Viewer
Location:
16q22.1
Exon count:
19
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (67326815..67385206)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (67360718..67419107)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene pleckstrin homology and RhoGEF domain containing G4 Neighboring gene potassium channel tetramerization domain containing 19 Neighboring gene RN7SK pseudogene 118 Neighboring gene RNA, U1 small nuclear 123, pseudogene Neighboring gene tubulin polymerization promoting protein family member 3 Neighboring gene zinc finger DHHC-type containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ11004

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
leucine-rich repeat-containing protein 36
Names
ROR gamma binding protein 70
heat shock regulated 2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001161575.2NP_001155047.1  leucine-rich repeat-containing protein 36 isoform 2

    See identical proteins and their annotated locations for NP_001155047.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AK297329, AY313780, BC018031, BP294008
    Consensus CDS
    CCDS58474.1
    UniProtKB/Swiss-Prot
    Q1X8D7
    UniProtKB/TrEMBL
    B7Z4G3
    Related
    ENSP00000455103.1, ENST00000563189.5
    Conserved Domains (1) summary
    pfam03962
    Location:484559
    Mnd1; Mnd1 family
  2. NM_018296.6NP_060766.5  leucine-rich repeat-containing protein 36 isoform 1

    See identical proteins and their annotated locations for NP_060766.5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC009061, BC018031, BC026156
    Consensus CDS
    CCDS32467.1
    UniProtKB/Swiss-Prot
    Q1X8D7
    Related
    ENSP00000329943.6, ENST00000329956.11
    Conserved Domains (3) summary
    sd00031
    Location:2651
    LRR_1; leucine-rich repeat [structural motif]
    pfam12799
    Location:5091
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:2684
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    67326815..67385206
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005256026.2XP_005256083.1  leucine-rich repeat-containing protein 36 isoform X3

    Conserved Domains (3) summary
    sd00031
    Location:2651
    LRR_1; leucine-rich repeat [structural motif]
    pfam12799
    Location:5091
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:2684
    LRR_8; Leucine rich repeat
  2. XM_011523203.1XP_011521505.1  leucine-rich repeat-containing protein 36 isoform X8

    Conserved Domains (4) summary
    sd00031
    Location:2651
    LRR_1; leucine-rich repeat [structural motif]
    cl11869
    Location:132250
    Csc2_I-D; CRISPR/Cas system-associated protein Csc2
    pfam12799
    Location:5091
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:2684
    LRR_8; Leucine rich repeat
  3. XM_005256028.1XP_005256085.1  leucine-rich repeat-containing protein 36 isoform X6

    See identical proteins and their annotated locations for XP_005256085.1

    Conserved Domains (1) summary
    pfam03962
    Location:437512
    Mnd1; Mnd1 family
  4. XM_017023401.1XP_016878890.1  leucine-rich repeat-containing protein 36 isoform X11

  5. XM_017023402.1XP_016878891.1  leucine-rich repeat-containing protein 36 isoform X12

  6. XM_005256025.2XP_005256082.1  leucine-rich repeat-containing protein 36 isoform X2

    Conserved Domains (3) summary
    sd00031
    Location:2651
    LRR_1; leucine-rich repeat [structural motif]
    pfam12799
    Location:5091
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:2684
    LRR_8; Leucine rich repeat
  7. XM_005256027.2XP_005256084.1  leucine-rich repeat-containing protein 36 isoform X4

    See identical proteins and their annotated locations for XP_005256084.1

    Conserved Domains (3) summary
    sd00031
    Location:2651
    LRR_1; leucine-rich repeat [structural motif]
    pfam12799
    Location:5091
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:2684
    LRR_8; Leucine rich repeat
  8. XM_017023400.2XP_016878889.1  leucine-rich repeat-containing protein 36 isoform X1

    Conserved Domains (3) summary
    sd00031
    Location:2651
    LRR_1; leucine-rich repeat [structural motif]
    pfam12799
    Location:5091
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:2684
    LRR_8; Leucine rich repeat
  9. XM_011523200.1XP_011521502.1  leucine-rich repeat-containing protein 36 isoform X5

    See identical proteins and their annotated locations for XP_011521502.1

    Conserved Domains (3) summary
    sd00031
    Location:2651
    LRR_1; leucine-rich repeat [structural motif]
    pfam12799
    Location:5091
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:2684
    LRR_8; Leucine rich repeat
  10. XM_011523206.3XP_011521508.1  leucine-rich repeat-containing protein 36 isoform X10

    Conserved Domains (3) summary
    sd00031
    Location:2651
    LRR_1; leucine-rich repeat [structural motif]
    pfam12799
    Location:5091
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:2684
    LRR_8; Leucine rich repeat
  11. XM_011523202.2XP_011521504.1  leucine-rich repeat-containing protein 36 isoform X7

    Conserved Domains (1) summary
    pfam03962
    Location:436511
    Mnd1; Mnd1 family
  12. XM_011523205.1XP_011521507.1  leucine-rich repeat-containing protein 36 isoform X9

    See identical proteins and their annotated locations for XP_011521507.1

    Conserved Domains (1) summary
    cl27210
    Location:363438
    Mnd1; Mnd1 family
  13. XM_011523201.1XP_011521503.1  leucine-rich repeat-containing protein 36 isoform X6

    See identical proteins and their annotated locations for XP_011521503.1

    Conserved Domains (1) summary
    pfam03962
    Location:437512
    Mnd1; Mnd1 family
  14. XM_011523204.1XP_011521506.1  leucine-rich repeat-containing protein 36 isoform X9

    See identical proteins and their annotated locations for XP_011521506.1

    Conserved Domains (1) summary
    cl27210
    Location:363438
    Mnd1; Mnd1 family
  15. XM_024450338.1XP_024306106.1  leucine-rich repeat-containing protein 36 isoform X9

    Conserved Domains (1) summary
    cl27210
    Location:363438
    Mnd1; Mnd1 family

RNA

  1. XR_243416.2 RNA Sequence

  2. XR_429723.1 RNA Sequence

Support Center