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TMEM140 transmembrane protein 140 [ Homo sapiens (human) ]

Gene ID: 55281, updated on 21-Dec-2019

Summary

Official Symbol
TMEM140provided by HGNC
Official Full Name
transmembrane protein 140provided by HGNC
Primary source
HGNC:HGNC:21870
See related
Ensembl:ENSG00000146859
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in fat (RPKM 20.1), lung (RPKM 18.2) and 25 other tissues See more
Orthologs

Genomic context

See TMEM140 in Genome Data Viewer
Location:
7q33
Exon count:
2
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (135148072..135166215)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (134832766..134850967)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene caldesmon 1 Neighboring gene ATP/GTP binding protein like 3 Neighboring gene cell cycle regulator of NHEJ Neighboring gene RNF14 pseudogene 4 Neighboring gene WD repeat domain 91 Neighboring gene microRNA 6509 Neighboring gene stimulated by retinoic acid 8

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ11000

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018295.5NP_060765.4  transmembrane protein 140

    See identical proteins and their annotated locations for NP_060765.4

    Status: VALIDATED

    Source sequence(s)
    AC083862, BU683951, DC323016
    Consensus CDS
    CCDS5837.1
    UniProtKB/Swiss-Prot
    Q9NV12
    Related
    ENSP00000275767.2, ENST00000275767.3
    Conserved Domains (1) summary
    pfam14985
    Location:6185
    TM140; TM140 protein family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    135148072..135166215
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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