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SLC47A1 solute carrier family 47 member 1 [ Homo sapiens (human) ]

Gene ID: 55244, updated on 1-Jun-2020

Summary

Official Symbol
SLC47A1provided by HGNC
Official Full Name
solute carrier family 47 member 1provided by HGNC
Primary source
HGNC:HGNC:25588
See related
Ensembl:ENSG00000142494 MIM:609832
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MATE1
Summary
This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008]
Expression
Biased expression in adrenal (RPKM 59.0), kidney (RPKM 50.0) and 6 other tissues See more
Orthologs

Genomic context

See SLC47A1 in Genome Data Viewer
Location:
17p11.2
Exon count:
17
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (19533854..19579034)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (19437167..19482346)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene ribosomal protein L17 pseudogene 43 Neighboring gene tRNA-Trp (anticodon CCA) 2-1 Neighboring gene uncharacterized LOC105371578 Neighboring gene small nucleolar RNA, H/ACA box 59B Neighboring gene SLC47A1 pseudogene 1 Neighboring gene MT-ND1 pseudogene 14

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10847, MGC64822

Gene Ontology Provided by GOA

Function Evidence Code Pubs
amide transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
antiporter activity IEA
Inferred from Electronic Annotation
more info
 
transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
xenobiotic transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
amide transport IEA
Inferred from Electronic Annotation
more info
 
cation transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
organic cation transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transmembrane transport TAS
Traceable Author Statement
more info
 
xenobiotic transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 
vesicle IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
multidrug and toxin extrusion protein 1
Names
MATE-1
hMATE-1
multidrug and toxin extrusion 1
solute carrier family 47 (multidrug and toxin extrusion), member 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018242.3NP_060712.2  multidrug and toxin extrusion protein 1

    See identical proteins and their annotated locations for NP_060712.2

    Status: VALIDATED

    Source sequence(s)
    AC025627
    Consensus CDS
    CCDS11209.1
    UniProtKB/Swiss-Prot
    Q96FL8
    Related
    ENSP00000270570.4, ENST00000270570.8
    Conserved Domains (1) summary
    cd13132
    Location:34468
    MATE_eukaryotic; Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    19533854..19579034
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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