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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029370.2Â RefSeqGene
- Range
-
5467..42998
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001193397.2 → NP_001180326.1  serine/threonine-protein phosphatase 2A activator isoform e
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) contains a different first exon, which results in the use of an in-frame downstream start codon, and lacks an alternate coding segment, compared to variant 1. The resulting protein (isoform e) is shorter when compared to isoform a.
- Source sequence(s)
-
AL158151, CD630703, DA052599, X73478
- Consensus CDS
-
CCDS75917.1
- UniProtKB/Swiss-Prot
-
Q15257
- UniProtKB/TrEMBL
-
F6WIT2
- Related
- ENSP00000394338.3, ENST00000452489.6
- Conserved Domains (1) summary
-
- pfam03095
Location:1 → 282
- PTPA; Phosphotyrosyl phosphate activator (PTPA) protein
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NM_001271832.2 → NP_001258761.1  serine/threonine-protein phosphatase 2A activator isoform f
See identical proteins and their annotated locations for NP_001258761.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) lacks two consecutive exons in the coding region, compared to variant 1. The resulting isoform (f) lacks an internal segment, compared to isoform a.
- Source sequence(s)
-
AL158151
- Consensus CDS
-
CCDS65156.1
- UniProtKB/Swiss-Prot
-
Q15257
- Related
- ENSP00000349726.4, ENST00000357197.8
- Conserved Domains (1) summary
-
- pfam03095
Location:26 → 288
- PTPA; Phosphotyrosyl phosphate activator (PTPA) protein
-
NM_021131.5 → NP_066954.2  serine/threonine-protein phosphatase 2A activator isoform b
See identical proteins and their annotated locations for NP_066954.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR and lacks an in-frame segment of the coding region, compared to variant 1. Variants 2 and 3 encode a shorter protein (isoform b), also known as isoform alpha, that is missing an internal segment compared to isoform a.
- Source sequence(s)
-
AL158151, BC002545, DB009663, X73478
- Consensus CDS
-
CCDS6920.1
- UniProtKB/Swiss-Prot
-
Q15257
- Related
- ENSP00000351885.5, ENST00000358994.9
- Conserved Domains (1) summary
-
- pfam03095
Location:26 → 317
- PTPA; Phosphotyrosyl phosphate activator (PTPA) protein
-
NM_178000.3 → NP_821067.1  serine/threonine-protein phosphatase 2A activator isoform b
See identical proteins and their annotated locations for NP_821067.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks one of the coding exons compared to transcript variant 1. It maintains the reading frame and encodes a protein (isoform b), also known as isoform alpha, that is missing an internal segment of the protein compared to isoform a. Variants 2 and 3 encode the same isoform.
- Source sequence(s)
-
AL158151
- Consensus CDS
-
CCDS6920.1
- UniProtKB/Swiss-Prot
-
Q15257
- Related
- ENSP00000377036.2, ENST00000393370.7
- Conserved Domains (1) summary
-
- pfam03095
Location:26 → 317
- PTPA; Phosphotyrosyl phosphate activator (PTPA) protein
-
NM_178001.3 → NP_821068.1  serine/threonine-protein phosphatase 2A activator isoform a
See identical proteins and their annotated locations for NP_821068.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript. It encodes the longest protein (isoform a), also known as isoform beta.
- Source sequence(s)
-
AL158151
- UniProtKB/Swiss-Prot
- Q15257, Q9NNZ9
- Related
- ENSP00000337448.1, ENST00000337738.6
- Conserved Domains (1) summary
-
- pfam03095
Location:26 → 351
- PTPA; Phosphotyrosyl phosphate activator (PTPA) protein
-
NM_178003.3 → NP_821070.1  serine/threonine-protein phosphatase 2A activator isoform d
See identical proteins and their annotated locations for NP_821070.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter protein (isoform d), also known as isoform epsilon, that is missing an internal segment compared to isoform a.
- Source sequence(s)
-
AL158151
- UniProtKB/Swiss-Prot
-
Q15257
- Related
- ENSP00000347109.3, ENST00000355007.7
- Conserved Domains (1) summary
-
- pfam03095
Location:26 → 275
- PTPA; Phosphotyrosyl phosphate activator (PTPA) protein
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000009.12Â Reference GRCh38.p14 Primary Assembly
- Range
-
129110950..129148946
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047423560.1 → XP_047279516.1  serine/threonine-protein phosphatase 2A activator isoform X4
-
XM_011518838.3 → XP_011517140.1  serine/threonine-protein phosphatase 2A activator isoform X5
- Conserved Domains (1) summary
-
- pfam03095
Location:76 → 337
- PTPA; Phosphotyrosyl phosphate activator (PTPA) protein
-
XM_047423559.1 → XP_047279515.1  serine/threonine-protein phosphatase 2A activator isoform X1
-
XM_011518834.3 → XP_011517136.1  serine/threonine-protein phosphatase 2A activator isoform X2
- Conserved Domains (1) summary
-
- pfam03095
Location:76 → 355
- PTPA; Phosphotyrosyl phosphate activator (PTPA) protein
-
XM_011518836.3 → XP_011517138.1  serine/threonine-protein phosphatase 2A activator isoform X3
- Conserved Domains (1) summary
-
- pfam03095
Location:76 → 326
- PTPA; Phosphotyrosyl phosphate activator (PTPA) protein
Alternate T2T-CHM13v2.0
Genomic
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NC_060933.1Â Alternate T2T-CHM13v2.0
- Range
-
141314397..141352390
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_178002.1: Suppressed sequence
- Description
- NM_178002.1: This RefSeq was permanently suppressed because currently there is insufficient support for this transcript variant and PMID:10880964 indicates that the encoded isoform may not be functional.