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ZNF532 zinc finger protein 532 [ Homo sapiens (human) ]

Gene ID: 55205, updated on 7-Apr-2025

Summary

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Official Symbol
ZNF532provided by HGNC
Official Full Name
zinc finger protein 532provided by HGNC
Primary source
HGNC:HGNC:30940
See related
Ensembl:ENSG00000074657 MIM:619066; AllianceGenome:HGNC:30940
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Expression
Ubiquitous expression in endometrium (RPKM 20.9), prostate (RPKM 17.9) and 22 other tissues See more
Orthologs
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Genomic context

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See ZNF532 in Genome Data Viewer
Location:
18q21.32
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (58862924..58986480)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (59064004..59187774)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (56530156..56653712)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene VISTA enhancer hs1397 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56475059-56476049 Neighboring gene U8 small nucleolar RNA Neighboring gene RNA, U6 small nuclear 219, pseudogene Neighboring gene long intergenic non-protein coding RNA 1926 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56513039-56513851 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56513852-56514664 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56514665-56515477 Neighboring gene Sharpr-MPRA regulatory region 466 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr18:56529025-56529566 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56529567-56530106 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56537205-56538186 Neighboring gene H3K27ac hESC enhancer GRCh37_chr18:56556548-56557048 Neighboring gene H3K27ac hESC enhancer GRCh37_chr18:56557049-56557549 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr18:56559638-56560464 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56582766-56583276 Neighboring gene RNA, U2 small nuclear 69, pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr18:56635193-56636106 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr18:56650842-56652041 Neighboring gene O-acyltransferase like, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9489 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56716067-56717037 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56717038-56718007 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr18:56729547-56730746 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13406 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13407 Neighboring gene NANOG hESC enhancer GRCh37_chr18:56758336-56758837 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9490 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13408 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13409 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9491 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13410 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13411 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13412 Neighboring gene SEC11 homolog C, signal peptidase complex subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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Related articles in PubMed

  1. Ectopic protein interactions within BRD4-chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma. Alekseyenko AA, et al. Proc Natl Acad Sci U S A, 2017 May 23. PMID 28484033, Free PMC Article
  2. Foxhead box D1 promotes the partial epithelial-to-mesenchymal transition of laryngeal squamous cell carcinoma cells via transcriptionally activating the expression of zinc finger protein 532. Fan L, et al. Bioengineered, 2022 Feb. PMID 35112956, Free PMC Article
  3. NUT carcinoma of the parotid gland: report of two cases, one with a rare ZNF532-NUTM1 fusion. Chen M, et al. Virchows Arch, 2022 Apr. PMID 35064291
  4. circZNF532 promotes endothelial-to-mesenchymal transition in diabetic retinopathy by recruiting TAF15 to stabilize PIK3CD. Fu XL, et al. Endocr J, 2024 Jul 12. PMID 38811189
  5. CircZNF532 knockdown protects retinal pigment epithelial cells against high glucose-induced apoptosis and pyroptosis by regulating the miR-20b-5p/STAT3 axis. Liang GH, et al. J Diabetes Investig, 2022 May. PMID 34839589, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. circZNF532 promotes endothelial-to-mesenchymal transition in diabetic retinopathy by recruiting TAF15 to stabilize PIK3CD.
    Title: circZNF532 promotes endothelial-to-mesenchymal transition in diabetic retinopathy by recruiting TAF15 to stabilize PIK3CD.
  2. CircZNF532 knockdown protects retinal pigment epithelial cells against high glucose-induced apoptosis and pyroptosis by regulating the miR-20b-5p/STAT3 axis.
    Title: CircZNF532 knockdown protects retinal pigment epithelial cells against high glucose-induced apoptosis and pyroptosis by regulating the miR-20b-5p/STAT3 axis.
  3. NUT carcinoma of the parotid gland: report of two cases, one with a rare ZNF532-NUTM1 fusion.
    Title: NUT carcinoma of the parotid gland: report of two cases, one with a rare ZNF532-NUTM1 fusion.
  4. Foxhead box D1 promotes the partial epithelial-to-mesenchymal transition of laryngeal squamous cell carcinoma cells via transcriptionally activating the expression of zinc finger protein 532.
    Title: Foxhead box D1 promotes the partial epithelial-to-mesenchymal transition of laryngeal squamous cell carcinoma cells via transcriptionally activating the expression of zinc finger protein 532.
  5. The authors discovered ZNF532 associated with BRD4-NUT in NMC patient cells. ChIP sequencing revealed the formation of ZNF532-NUT-associated hyperacetylated megadomains, distinctly localized but otherwise analogous to those found in BRD4-NUT patient cells.
    Title: Ectopic protein interactions within BRD4-chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma.
  6. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ10697

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity NAS
Non-traceable Author Statement
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 532

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001318726.2 → NP_001305655.1  zinc finger protein 532 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-9 all encode the same isoform (a).
    Source sequence(s)
    AA807005, AK001559, AK128058, BC130618, DB299524
    Consensus CDS
    CCDS11969.1
    UniProtKB/Swiss-Prot
    Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
    UniProtKB/TrEMBL
    B3KXW2
    Related
    ENSP00000468532.1, ENST00000591083.5
    Conserved Domains (4) summary
    sd00017
    Location:1027 → 1047
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02591
    Location:784 → 819
    zf-RING_7; C4-type zinc ribbon domain
    pfam13912
    Location:1265 → 1286
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:1199 → 1227
    zf-C2H2_11; zinc-finger C2H2-type

  2. NM_001318727.2 → NP_001305656.1  zinc finger protein 532 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-9 all encode the same isoform (a).
    Source sequence(s)
    AA807005, AB046849, AC090233, AK001559, DA108216, DB299524
    Consensus CDS
    CCDS11969.1
    UniProtKB/Swiss-Prot
    Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
    UniProtKB/TrEMBL
    B3KXW2
    Related
    ENSP00000466007.1, ENST00000589288.5
    Conserved Domains (4) summary
    sd00017
    Location:1027 → 1047
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02591
    Location:784 → 819
    zf-RING_7; C4-type zinc ribbon domain
    pfam13912
    Location:1265 → 1286
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:1199 → 1227
    zf-C2H2_11; zinc-finger C2H2-type

  3. NM_001318728.2 → NP_001305657.1  zinc finger protein 532 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-9 all encode the same isoform (a).
    Source sequence(s)
    AA807005, AK001559, BC036366, DA191371, DB299524
    Consensus CDS
    CCDS11969.1
    UniProtKB/Swiss-Prot
    Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
    UniProtKB/TrEMBL
    B3KXW2
    Related
    ENSP00000465709.1, ENST00000591230.5
    Conserved Domains (4) summary
    sd00017
    Location:1027 → 1047
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02591
    Location:784 → 819
    zf-RING_7; C4-type zinc ribbon domain
    pfam13912
    Location:1265 → 1286
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:1199 → 1227
    zf-C2H2_11; zinc-finger C2H2-type

  4. NM_001353525.2 → NP_001340454.1  zinc finger protein 532 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5), as well as variants 1-4 and 6-9, encodes isoform a.
    Source sequence(s)
    AC040963, AC090233
    Consensus CDS
    CCDS11969.1
    UniProtKB/Swiss-Prot
    Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
    UniProtKB/TrEMBL
    B3KXW2
    Conserved Domains (4) summary
    sd00017
    Location:1027 → 1047
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02591
    Location:784 → 819
    zf-RING_7; C4-type zinc ribbon domain
    pfam13912
    Location:1265 → 1286
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:1199 → 1227
    zf-C2H2_11; zinc-finger C2H2-type

  5. NM_001353526.2 → NP_001340455.1  zinc finger protein 532 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6), as well as variants 1-5 and 7-9, encodes isoform a.
    Source sequence(s)
    AC040963, AC090233
    Consensus CDS
    CCDS11969.1
    UniProtKB/Swiss-Prot
    Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
    UniProtKB/TrEMBL
    B3KXW2
    Conserved Domains (4) summary
    sd00017
    Location:1027 → 1047
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02591
    Location:784 → 819
    zf-RING_7; C4-type zinc ribbon domain
    pfam13912
    Location:1265 → 1286
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:1199 → 1227
    zf-C2H2_11; zinc-finger C2H2-type

  6. NM_001353527.2 → NP_001340456.1  zinc finger protein 532 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7), as well as variants 1-6, 8, and 9, encodes isoform a.
    Source sequence(s)
    AC040963, AC090233
    Consensus CDS
    CCDS11969.1
    UniProtKB/Swiss-Prot
    Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
    UniProtKB/TrEMBL
    B3KXW2
    Conserved Domains (4) summary
    sd00017
    Location:1027 → 1047
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02591
    Location:784 → 819
    zf-RING_7; C4-type zinc ribbon domain
    pfam13912
    Location:1265 → 1286
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:1199 → 1227
    zf-C2H2_11; zinc-finger C2H2-type

  7. NM_001353528.2 → NP_001340457.1  zinc finger protein 532 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8), as well as variants 1-7 and 9, encodes isoform a.
    Source sequence(s)
    AC040963, AC090233
    Consensus CDS
    CCDS11969.1
    UniProtKB/Swiss-Prot
    Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
    UniProtKB/TrEMBL
    B3KXW2
    Conserved Domains (4) summary
    sd00017
    Location:1027 → 1047
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02591
    Location:784 → 819
    zf-RING_7; C4-type zinc ribbon domain
    pfam13912
    Location:1265 → 1286
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:1199 → 1227
    zf-C2H2_11; zinc-finger C2H2-type

  8. NM_001353529.2 → NP_001340458.1  zinc finger protein 532 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9), as well as variants 1-8, encodes isoform a.
    Source sequence(s)
    AC040963, AC090233
    Consensus CDS
    CCDS11969.1
    UniProtKB/Swiss-Prot
    Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
    UniProtKB/TrEMBL
    B3KXW2
    Conserved Domains (4) summary
    sd00017
    Location:1027 → 1047
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02591
    Location:784 → 819
    zf-RING_7; C4-type zinc ribbon domain
    pfam13912
    Location:1265 → 1286
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:1199 → 1227
    zf-C2H2_11; zinc-finger C2H2-type

  9. NM_001353530.2 → NP_001340459.1  zinc finger protein 532 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10), as well as variants 11 and 12, encodes isoform b.
    Source sequence(s)
    AC040963, AC090233
    UniProtKB/TrEMBL
    B3KXW2
    Conserved Domains (2) summary
    sd00017
    Location:1027 → 1047
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam16622
    Location:1195 → 1223
    zf-C2H2_11; zinc-finger C2H2-type

  10. NM_001353531.2 → NP_001340460.1  zinc finger protein 532 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11), as well as variants 10 and 12, encodes isoform b.
    Source sequence(s)
    AC040963, AC090233
    UniProtKB/TrEMBL
    B3KXW2
    Conserved Domains (2) summary
    sd00017
    Location:1027 → 1047
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam16622
    Location:1195 → 1223
    zf-C2H2_11; zinc-finger C2H2-type

  11. NM_001353532.2 → NP_001340461.1  zinc finger protein 532 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12), as well as variants 10 and 11, encodes isoform b.
    Source sequence(s)
    AC040963, AC090233
    UniProtKB/TrEMBL
    B3KXW2
    Conserved Domains (2) summary
    sd00017
    Location:1027 → 1047
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam16622
    Location:1195 → 1223
    zf-C2H2_11; zinc-finger C2H2-type

  12. NM_001353533.2 → NP_001340462.1  zinc finger protein 532 isoform c

    Status: VALIDATED

    Source sequence(s)
    AC040963, AC090233
    UniProtKB/TrEMBL
    B3KXW2
    Conserved Domains (3) summary
    sd00017
    Location:968 → 988
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13912
    Location:1206 → 1227
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:1142 → 1168
    zf-C2H2_11; zinc-finger C2H2-type

  13. NM_001353534.2 → NP_001340463.1  zinc finger protein 532 isoform d

    Status: VALIDATED

    Source sequence(s)
    AC040963, AC090233
    UniProtKB/TrEMBL
    B3KXW2
    Conserved Domains (2) summary
    sd00017
    Location:968 → 988
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam16622
    Location:1136 → 1164
    zf-C2H2_11; zinc-finger C2H2-type

  14. NM_001353535.2 → NP_001340464.1  zinc finger protein 532 isoform e

    Status: VALIDATED

    Description
    Transcript Variant: This variant (15), as well as variant 16, encodes isoform e.
    Source sequence(s)
    AC040963, AC090233
    UniProtKB/TrEMBL
    B3KXW2
    Conserved Domains (3) summary
    sd00017
    Location:853 → 873
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13912
    Location:1090 → 1112
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:1025 → 1053
    zf-C2H2_11; zinc-finger C2H2-type

  15. NM_001353536.2 → NP_001340465.1  zinc finger protein 532 isoform e

    Status: VALIDATED

    Description
    Transcript Variant: This variant (16), as well as variant 15, encodes isoform e.
    Source sequence(s)
    AC040963, AC090233
    UniProtKB/TrEMBL
    B3KXW2
    Conserved Domains (3) summary
    sd00017
    Location:853 → 873
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13912
    Location:1090 → 1112
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:1025 → 1053
    zf-C2H2_11; zinc-finger C2H2-type

  16. NM_001353537.2 → NP_001340466.1  zinc finger protein 532 isoform f

    Status: VALIDATED

    Source sequence(s)
    AC040963, AC090233
    UniProtKB/TrEMBL
    B3KXW2
    Conserved Domains (3) summary
    sd00017
    Location:853 → 873
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13912
    Location:1086 → 1108
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:1021 → 1049
    zf-C2H2_11; zinc-finger C2H2-type

  17. NM_001353538.2 → NP_001340467.1  zinc finger protein 532 isoform g

    Status: VALIDATED

    Source sequence(s)
    AC040963, AC090233
    Conserved Domains (3) summary
    sd00017
    Location:756 → 778
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13912
    Location:996 → 1018
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:931 → 959
    zf-C2H2_11; zinc-finger C2H2-type

  18. NM_001375912.1 → NP_001362841.1  zinc finger protein 532 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC040963, AC090233
    Consensus CDS
    CCDS11969.1
    UniProtKB/Swiss-Prot
    Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
    UniProtKB/TrEMBL
    B3KXW2
    Related
    ENSP00000468238.1, ENST00000591808.6
    Conserved Domains (4) summary
    sd00017
    Location:1027 → 1047
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02591
    Location:784 → 819
    zf-RING_7; C4-type zinc ribbon domain
    pfam13912
    Location:1265 → 1286
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:1199 → 1227
    zf-C2H2_11; zinc-finger C2H2-type

  19. NM_001375913.1 → NP_001362842.1  zinc finger protein 532 isoform c

    Status: VALIDATED

    Source sequence(s)
    AC040963, AC090233
    UniProtKB/TrEMBL
    B3KXW2
    Conserved Domains (3) summary
    sd00017
    Location:968 → 988
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13912
    Location:1206 → 1227
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:1142 → 1168
    zf-C2H2_11; zinc-finger C2H2-type

  20. NM_018181.6 → NP_060651.2  zinc finger protein 532 isoform a

    See identical proteins and their annotated locations for NP_060651.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1-9 all encode the same isoform (a).
    Source sequence(s)
    AA807005, AF295077, AK128058, BE219488, BF591635
    Consensus CDS
    CCDS11969.1
    UniProtKB/Swiss-Prot
    Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
    UniProtKB/TrEMBL
    B3KXW2
    Related
    ENSP00000338217.4, ENST00000336078.8
    Conserved Domains (4) summary
    sd00017
    Location:1027 → 1047
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02591
    Location:784 → 819
    zf-RING_7; C4-type zinc ribbon domain
    pfam13912
    Location:1265 → 1286
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:1199 → 1227
    zf-C2H2_11; zinc-finger C2H2-type

RNA

  1. NR_148459.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC040963, AC090233

  2. NR_148460.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC040963, AC090233

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    58862924..58986480
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047437584.1 → XP_047293540.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  2. XM_047437592.1 → XP_047293548.1  zinc finger protein 532 isoform X4

    UniProtKB/TrEMBL
    B3KXW2

  3. XM_047437606.1 → XP_047293562.1  zinc finger protein 532 isoform X15

  4. XM_047437607.1 → XP_047293563.1  zinc finger protein 532 isoform X16

  5. XM_047437599.1 → XP_047293555.1  zinc finger protein 532 isoform X6

    UniProtKB/TrEMBL
    B3KXW2

  6. XM_017025810.2 → XP_016881299.1  zinc finger protein 532 isoform X2

    UniProtKB/TrEMBL
    B3KXW2

  7. XM_047437588.1 → XP_047293544.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  8. XM_047437593.1 → XP_047293549.1  zinc finger protein 532 isoform X4

    UniProtKB/TrEMBL
    B3KXW2

  9. XM_047437598.1 → XP_047293554.1  zinc finger protein 532 isoform X5

    UniProtKB/TrEMBL
    B3KXW2

  10. XM_017025815.2 → XP_016881304.1  zinc finger protein 532 isoform X7

    UniProtKB/Swiss-Prot
    Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
    UniProtKB/TrEMBL
    B3KXW2
    Conserved Domains (4) summary
    sd00017
    Location:1027 → 1047
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02591
    Location:784 → 819
    zf-RING_7; C4-type zinc ribbon domain
    pfam13912
    Location:1265 → 1286
    zf-C2H2_6; C2H2-type zinc finger
    pfam16622
    Location:1199 → 1227
    zf-C2H2_11; zinc-finger C2H2-type

  11. XM_047437603.1 → XP_047293559.1  zinc finger protein 532 isoform X11

    UniProtKB/TrEMBL
    B3KXW2

  12. XM_047437608.1 → XP_047293564.1  zinc finger protein 532 isoform X17

  13. XM_047437591.1 → XP_047293547.1  zinc finger protein 532 isoform X4

    UniProtKB/TrEMBL
    B3KXW2

  14. XM_047437605.1 → XP_047293561.1  zinc finger protein 532 isoform X15

  15. XM_047437596.1 → XP_047293552.1  zinc finger protein 532 isoform X5

    UniProtKB/TrEMBL
    B3KXW2

  16. XM_047437581.1 → XP_047293537.1  zinc finger protein 532 isoform X2

    UniProtKB/TrEMBL
    B3KXW2

  17. XM_047437586.1 → XP_047293542.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  18. XM_047437600.1 → XP_047293556.1  zinc finger protein 532 isoform X7

    UniProtKB/Swiss-Prot
    Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
    UniProtKB/TrEMBL
    B3KXW2

  19. XM_047437582.1 → XP_047293538.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  20. XM_047437589.1 → XP_047293545.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  21. XM_047437585.1 → XP_047293541.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  22. XM_047437587.1 → XP_047293543.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  23. XM_047437594.1 → XP_047293550.1  zinc finger protein 532 isoform X4

    UniProtKB/TrEMBL
    B3KXW2

  24. XM_017025811.3 → XP_016881300.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  25. XM_047437590.1 → XP_047293546.1  zinc finger protein 532 isoform X4

    UniProtKB/TrEMBL
    B3KXW2

  26. XM_047437595.1 → XP_047293551.1  zinc finger protein 532 isoform X5

    UniProtKB/TrEMBL
    B3KXW2

  27. XM_047437583.1 → XP_047293539.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  28. XM_047437597.1 → XP_047293553.1  zinc finger protein 532 isoform X5

    UniProtKB/TrEMBL
    B3KXW2

  29. XM_047437601.1 → XP_047293557.1  zinc finger protein 532 isoform X7

    UniProtKB/Swiss-Prot
    Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
    UniProtKB/TrEMBL
    B3KXW2

  30. XM_047437609.1 → XP_047293565.1  zinc finger protein 532 isoform X19

  31. XM_017025830.2 → XP_016881319.1  zinc finger protein 532 isoform X14

  32. XM_017025824.2 → XP_016881313.1  zinc finger protein 532 isoform X9

    UniProtKB/TrEMBL
    B3KXW2

  33. XM_017025823.2 → XP_016881312.1  zinc finger protein 532 isoform X8

    UniProtKB/TrEMBL
    B3KXW2

  34. XM_017025829.2 → XP_016881318.1  zinc finger protein 532 isoform X13

  35. XM_017025809.2 → XP_016881298.1  zinc finger protein 532 isoform X1

    UniProtKB/TrEMBL
    B3KXW2

  36. XM_047437602.1 → XP_047293558.1  zinc finger protein 532 isoform X10

    UniProtKB/TrEMBL
    B3KXW2

  37. XM_047437604.1 → XP_047293560.1  zinc finger protein 532 isoform X12

    UniProtKB/TrEMBL
    B3KXW2

  38. XM_011526067.3 → XP_011524369.1  zinc finger protein 532 isoform X18

    Conserved Domains (2) summary
    sd00017
    Location:785 → 805
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12756
    Location:834 → 871
    zf-C2H2_2; C2H2 type zinc-finger (2 copies)

RNA

  1. XR_935229.3 RNA Sequence

  2. XR_007066180.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    59064004..59187774
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054318749.1 → XP_054174724.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  2. XM_054318757.1 → XP_054174732.1  zinc finger protein 532 isoform X4

    UniProtKB/TrEMBL
    B3KXW2

  3. XM_054318774.1 → XP_054174749.1  zinc finger protein 532 isoform X15

  4. XM_054318775.1 → XP_054174750.1  zinc finger protein 532 isoform X16

  5. XM_054318763.1 → XP_054174738.1  zinc finger protein 532 isoform X6

    UniProtKB/TrEMBL
    B3KXW2

  6. XM_054318745.1 → XP_054174720.1  zinc finger protein 532 isoform X2

    UniProtKB/TrEMBL
    B3KXW2

  7. XM_054318753.1 → XP_054174728.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  8. XM_054318758.1 → XP_054174733.1  zinc finger protein 532 isoform X4

    UniProtKB/TrEMBL
    B3KXW2

  9. XM_054318762.1 → XP_054174737.1  zinc finger protein 532 isoform X5

    UniProtKB/TrEMBL
    B3KXW2

  10. XM_054318767.1 → XP_054174742.1  zinc finger protein 532 isoform X7

    UniProtKB/Swiss-Prot
    Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
    UniProtKB/TrEMBL
    B3KXW2

  11. XM_054318769.1 → XP_054174744.1  zinc finger protein 532 isoform X11

    UniProtKB/TrEMBL
    B3KXW2

  12. XM_054318776.1 → XP_054174751.1  zinc finger protein 532 isoform X17

  13. XM_054318756.1 → XP_054174731.1  zinc finger protein 532 isoform X4

    UniProtKB/TrEMBL
    B3KXW2

  14. XM_054318773.1 → XP_054174748.1  zinc finger protein 532 isoform X15

  15. XM_054318744.1 → XP_054174719.1  zinc finger protein 532 isoform X2

    UniProtKB/TrEMBL
    B3KXW2

  16. XM_054318751.1 → XP_054174726.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  17. XM_054318764.1 → XP_054174739.1  zinc finger protein 532 isoform X7

    UniProtKB/Swiss-Prot
    Q4G0V6, Q7L7Z7, Q96QR7, Q9HCE3, Q9NVJ6
    UniProtKB/TrEMBL
    B3KXW2

  18. XM_054318747.1 → XP_054174722.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  19. XM_054318754.1 → XP_054174729.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  20. XM_054318750.1 → XP_054174725.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  21. XM_054318752.1 → XP_054174727.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  22. XM_054318759.1 → XP_054174734.1  zinc finger protein 532 isoform X4

    UniProtKB/TrEMBL
    B3KXW2

  23. XM_054318746.1 → XP_054174721.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  24. XM_054318755.1 → XP_054174730.1  zinc finger protein 532 isoform X4

    UniProtKB/TrEMBL
    B3KXW2

  25. XM_054318760.1 → XP_054174735.1  zinc finger protein 532 isoform X5

    UniProtKB/TrEMBL
    B3KXW2

  26. XM_054318748.1 → XP_054174723.1  zinc finger protein 532 isoform X3

    UniProtKB/TrEMBL
    B3KXW2

  27. XM_054318761.1 → XP_054174736.1  zinc finger protein 532 isoform X5

    UniProtKB/TrEMBL
    B3KXW2

  28. XM_054318778.1 → XP_054174753.1  zinc finger protein 532 isoform X19

  29. XM_054318772.1 → XP_054174747.1  zinc finger protein 532 isoform X14

  30. XM_054318766.1 → XP_054174741.1  zinc finger protein 532 isoform X9

    UniProtKB/TrEMBL
    B3KXW2

  31. XM_054318765.1 → XP_054174740.1  zinc finger protein 532 isoform X8

    UniProtKB/TrEMBL
    B3KXW2

  32. XM_054318771.1 → XP_054174746.1  zinc finger protein 532 isoform X13

  33. XM_054318743.1 → XP_054174718.1  zinc finger protein 532 isoform X1

    UniProtKB/TrEMBL
    B3KXW2

  34. XM_054318768.1 → XP_054174743.1  zinc finger protein 532 isoform X10

    UniProtKB/TrEMBL
    B3KXW2

  35. XM_054318770.1 → XP_054174745.1  zinc finger protein 532 isoform X12

    UniProtKB/TrEMBL
    B3KXW2

  36. XM_054318777.1 → XP_054174752.1  zinc finger protein 532 isoform X18

RNA

  1. XR_008485002.1 RNA Sequence

  2. XR_008485003.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9HCE3.2 GenPept UniProtKB/Swiss-Prot:Q9HCE3

Gene LinkOut

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