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EVA1B eva-1 homolog B [ Homo sapiens (human) ]

Gene ID: 55194, updated on 7-Jun-2020

Summary

Official Symbol
EVA1Bprovided by HGNC
Official Full Name
eva-1 homolog Bprovided by HGNC
Primary source
HGNC:HGNC:25558
See related
Ensembl:ENSG00000142694
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C1orf78; FAM176B
Expression
Broad expression in kidney (RPKM 6.9), fat (RPKM 6.6) and 23 other tissues See more
Orthologs

Genomic context

See EVA1B in Genome Data Viewer
Location:
1p34.3
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (36322030..36324154, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (36787631..36790567, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene thyroid hormone receptor associated protein 3 Neighboring gene Sharpr-MPRA regulatory regions 10257 and 14041 Neighboring gene Sharpr-MPRA regulatory region 2392 Neighboring gene SH3 domain containing 21 Neighboring gene serine/threonine kinase 40 Neighboring gene Sharpr-MPRA regulatory region 4421 Neighboring gene LSM10, U7 small nuclear RNA associated

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10647

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein eva-1 homolog B
Names
family with sequence similarity 176, member B
protein FAM176B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001304762.2NP_001291691.1  protein eva-1 homolog B

    See identical proteins and their annotated locations for NP_001291691.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AL591845, BC006241, BI193341, BU625845
    Consensus CDS
    CCDS406.1
    UniProtKB/Swiss-Prot
    Q9NVM1
    Conserved Domains (1) summary
    pfam14851
    Location:7151
    FAM176; FAM176 family
  2. NM_018166.2NP_060636.1  protein eva-1 homolog B

    See identical proteins and their annotated locations for NP_060636.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AK001509, AL591845, BC006241, BU625845
    Consensus CDS
    CCDS406.1
    UniProtKB/Swiss-Prot
    Q9NVM1
    Related
    ENSP00000270824.1, ENST00000270824.1
    Conserved Domains (1) summary
    pfam14851
    Location:7151
    FAM176; FAM176 family

RNA

  1. NR_130899.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and lacks an alternate internal exon compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant 1.
    Source sequence(s)
    AI829867, AL591845, BC006241, BI193341, BU625845

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    36322030..36324154 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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