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DNAJC17 DnaJ heat shock protein family (Hsp40) member C17 [ Homo sapiens (human) ]

Gene ID: 55192, updated on 4-Dec-2022

Summary

Official Symbol
DNAJC17provided by HGNC
Official Full Name
DnaJ heat shock protein family (Hsp40) member C17provided by HGNC
Primary source
HGNC:HGNC:25556
See related
Ensembl:ENSG00000104129 MIM:616844; AllianceGenome:HGNC:25556
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable RNA binding activity. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II and toxin transport. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in small intestine (RPKM 6.2), liver (RPKM 5.7) and 25 other tissues See more
Orthologs
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Genomic context

See DNAJC17 in Genome Data Viewer
Location:
15q15.1
Exon count:
11
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (40765161..40807473, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (38571183..38613497, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (41057359..41099671, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene regulator of microtubule dynamics 3 Neighboring gene uncharacterized LOC124903474 Neighboring gene SUMO2 pseudogene 15 Neighboring gene GTP cyclohydrolase I feedback regulator Neighboring gene chromosome 15 open reading frame 62 Neighboring gene zinc finger FYVE-type containing 19 Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 14D Neighboring gene Sharpr-MPRA regulatory region 7770 Neighboring gene SPINT1 antisense RNA 1 Neighboring gene serine peptidase inhibitor, Kunitz type 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10634

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in spliceosomal complex disassembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in toxin transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
part_of spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
dnaJ homolog subfamily C member 17
Names
DnaJ (Hsp40) homolog, subfamily C, member 17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018163.3NP_060633.1  dnaJ homolog subfamily C member 17

    See identical proteins and their annotated locations for NP_060633.1

    Status: VALIDATED

    Source sequence(s)
    AA834211, AC012476, AK001496, DA341962
    Consensus CDS
    CCDS10065.1
    UniProtKB/Swiss-Prot
    Q9NVM6
    Related
    ENSP00000220496.4, ENST00000220496.9
    Conserved Domains (2) summary
    cd12429
    Location:184247
    RRM_DNAJC17; RNA recognition motif in the DnaJ homolog subfamily C member 17
    pfam00226
    Location:1173
    DnaJ; DnaJ domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    40765161..40807473 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047432788.1XP_047288744.1  dnaJ homolog subfamily C member 17 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    38571183..38613497 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)