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RMDN3 regulator of microtubule dynamics 3 [ Homo sapiens (human) ]

Gene ID: 55177, updated on 21-Dec-2019

Summary

Official Symbol
RMDN3provided by HGNC
Official Full Name
regulator of microtubule dynamics 3provided by HGNC
Primary source
HGNC:HGNC:25550
See related
Ensembl:ENSG00000137824 MIM:611873
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RMD3; RMD-3; FAM82C; FAM82A2; ptpip51
Expression
Ubiquitous expression in small intestine (RPKM 16.9), lung (RPKM 14.6) and 25 other tissues See more
Orthologs

Genomic context

See RMDN3 in Genome Data Viewer
Location:
15q15.1
Exon count:
14
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (40735884..40755336, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (41028085..41047458, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene kinetochore scaffold 1 Neighboring gene RNA, 7SL, cytoplasmic 376, pseudogene Neighboring gene RAD51 antisense RNA 1 Neighboring gene RAD51 recombinase Neighboring gene SUMO2 pseudogene 15 Neighboring gene DnaJ heat shock protein family (Hsp40) member C17 Neighboring gene GTP cyclohydrolase I feedback regulator

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10579

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
cellular calcium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cell IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intercellular bridge IDA
Inferred from Direct Assay
more info
 
microtubule IEA
Inferred from Electronic Annotation
more info
 
mitochondrial outer membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
spindle pole IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
regulator of microtubule dynamics protein 3
Names
TCPTP-interacting protein 51
cerebral protein 10
family with sequence similarity 82, member A2
family with sequence similarity 82, member C
microtubule-associated protein
protein tyrosine phosphatase-interacting protein 51

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001304802.1NP_001291731.1  regulator of microtubule dynamics protein 3 isoform 1

    See identical proteins and their annotated locations for NP_001291731.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AA772280, AK092058, DA280017, DA592879
    Consensus CDS
    CCDS10063.1
    UniProtKB/Swiss-Prot
    Q96TC7
    UniProtKB/TrEMBL
    A0A024R9P6
    Related
    ENSP00000260385.6, ENST00000260385.10
    Conserved Domains (1) summary
    sd00006
    Location:362412
    TPR; TPR repeat [structural motif]
  2. NM_001323894.1NP_001310823.1  regulator of microtubule dynamics protein 3 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC012476
    Consensus CDS
    CCDS10063.1
    UniProtKB/Swiss-Prot
    Q96TC7
    UniProtKB/TrEMBL
    A0A024R9P6
    Conserved Domains (1) summary
    sd00006
    Location:362412
    TPR; TPR repeat [structural motif]
  3. NM_001323895.1NP_001310824.1  regulator of microtubule dynamics protein 3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC012476
    UniProtKB/Swiss-Prot
    Q96TC7
    Conserved Domains (1) summary
    sd00006
    Location:233283
    TPR; TPR repeat [structural motif]
  4. NM_001323896.1NP_001310825.1  regulator of microtubule dynamics protein 3 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC012476
  5. NM_001323897.1NP_001310826.1  regulator of microtubule dynamics protein 3 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC012476
  6. NM_018145.3NP_060615.1  regulator of microtubule dynamics protein 3 isoform 1

    See identical proteins and their annotated locations for NP_060615.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents transcript variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    BC063844, DA280017
    Consensus CDS
    CCDS10063.1
    UniProtKB/Swiss-Prot
    Q96TC7
    UniProtKB/TrEMBL
    A0A024R9P6
    Related
    ENSP00000342493.3, ENST00000338376.8
    Conserved Domains (1) summary
    sd00006
    Location:362412
    TPR; TPR repeat [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    40735884..40755336 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011521755.2XP_011520057.1  regulator of microtubule dynamics protein 3 isoform X1

    Related
    ENSP00000453535.1, ENST00000558232.5
    Conserved Domains (1) summary
    sd00006
    Location:156206
    TPR; TPR repeat [structural motif]
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