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KLHL11 kelch like family member 11 [ Homo sapiens (human) ]

Gene ID: 55175, updated on 8-Jul-2021

Summary

Official Symbol
KLHL11provided by HGNC
Official Full Name
kelch like family member 11provided by HGNC
Primary source
HGNC:HGNC:19008
See related
Ensembl:ENSG00000178502 MIM:619078
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in testis (RPKM 5.8), brain (RPKM 4.6) and 25 other tissues See more
Orthologs
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Genomic context

See KLHL11 in Genome Data Viewer
Location:
17q21.2
Exon count:
3
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (41848514..41865423, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (40004770..40021676, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene FKBP prolyl isomerase 10 Neighboring gene 5'-nucleotidase, cytosolic IIIB Neighboring gene kelch like family member 10 Neighboring gene ATP citrate lyase Neighboring gene outer dynein arm docking complex subunit 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10572, FLJ39096

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol TAS
Traceable Author Statement
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018143.3NP_060613.1  kelch-like protein 11 precursor

    See identical proteins and their annotated locations for NP_060613.1

    Status: VALIDATED

    Source sequence(s)
    AC125257, AK001434, BI463857
    Consensus CDS
    CCDS11411.1
    UniProtKB/Swiss-Prot
    Q9NVR0
    UniProtKB/TrEMBL
    A0A024R1T8
    Related
    ENSP00000314608.3, ENST00000319121.4
    Conserved Domains (5) summary
    smart00612
    Location:611657
    Kelch; Kelch domain
    PHA03098
    Location:90553
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:399439
    Kelch; KELCH repeat [structural motif]
    cd18241
    Location:71205
    BTB_POZ_KLHL11; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 11 (KLHL11)
    cd18451
    Location:200287
    BACK_KLHL11; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 11 (KLHL11)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    41848514..41865423 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_001752552.2 RNA Sequence

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