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XKR8 XK related 8 [ Homo sapiens (human) ]

Gene ID: 55113, updated on 1-Jun-2020

Summary

Official Symbol
XKR8provided by HGNC
Official Full Name
XK related 8provided by HGNC
Primary source
HGNC:HGNC:25508
See related
Ensembl:ENSG00000158156
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
XRG8; hXkr8
Expression
Ubiquitous expression in placenta (RPKM 5.8), bone marrow (RPKM 5.1) and 25 other tissues See more
Orthologs

Genomic context

See XKR8 in Genome Data Viewer
Location:
1p35.3
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (27959557..27968093)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (28286504..28294604)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene replication protein A2 Neighboring gene sphingomyelin phosphodiesterase acid like 3B Neighboring gene EYA transcriptional coactivator and phosphatase 3 Neighboring gene RNA, 7SL, cytoplasmic 559, pseudogene Neighboring gene signal peptidase complex subunit 2 pseudogene 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10307

Gene Ontology Provided by GOA

Process Evidence Code Pubs
apoptotic process involved in development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
engulfment of apoptotic cell IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
engulfment of apoptotic cell IDA
Inferred from Direct Assay
more info
PubMed 
phosphatidylserine exposure on apoptotic cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylserine exposure on apoptotic cell surface IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
XK-related protein 8
Names
X Kell blood group precursor-related family, member 8
X-linked Kx blood group related 8
XK, Kell blood group complex subunit-related family, member 8

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018053.4NP_060523.2  XK-related protein 8

    See identical proteins and their annotated locations for NP_060523.2

    Status: VALIDATED

    Source sequence(s)
    AL512288
    Consensus CDS
    CCDS315.1
    UniProtKB/Swiss-Prot
    Q9H6D3
    Related
    ENSP00000362991.5, ENST00000373884.6
    Conserved Domains (1) summary
    pfam09815
    Location:17344
    XK-related; XK-related protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    27959557..27968093
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011541679.3XP_011539981.1  XK-related protein 8 isoform X1

    Conserved Domains (1) summary
    pfam09815
    Location:218398
    XK-related; XK-related protein
  2. XM_011541680.3XP_011539982.1  XK-related protein 8 isoform X2

    Conserved Domains (1) summary
    pfam09815
    Location:182362
    XK-related; XK-related protein

RNA

  1. XR_946682.2 RNA Sequence

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