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CCDC186 coiled-coil domain containing 186 [ Homo sapiens (human) ]

Gene ID: 55088, updated on 11-Sep-2019

Summary

Official Symbol
CCDC186provided by HGNC
Official Full Name
coiled-coil domain containing 186provided by HGNC
Primary source
HGNC:HGNC:24349
See related
Ensembl:ENSG00000165813
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CCCP-1; C10orf118; golgin104
Expression
Ubiquitous expression in thyroid (RPKM 7.2), prostate (RPKM 7.0) and 25 other tissues See more
Orthologs

Genomic context

See CCDC186 in Genome Data Viewer
Location:
10q25.3
Exon count:
18
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (114120862..114174255, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (115880615..115934364, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene RNA, U6 small nuclear 709, pseudogene Neighboring gene ubiquitin conjugating enzyme E2 V1 pseudogene 5 Neighboring gene microRNA 2110 Neighboring gene tudor domain containing 1 Neighboring gene aurora kinase A pseudogene 2 Neighboring gene von Willebrand factor A domain containing 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ10188, FLJ35301, MGC118918, MGC129699

Gene Ontology Provided by GOA

Process Evidence Code Pubs
response to bacterium IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
coiled-coil domain-containing protein 186
Names
CTCL tumor antigen HD-CL-01/L14-2
CTCL tumor antigen L14-2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001321829.1NP_001308758.1  coiled-coil domain-containing protein 186 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AI672382, AK024739, AK094498, BC030557, BC100670, BX537964
    Consensus CDS
    CCDS7587.1
    UniProtKB/Swiss-Prot
    Q7Z3E2
    UniProtKB/TrEMBL
    Q496Y1
    Related
    ENSP00000498136.1, ENST00000648613.1
    Conserved Domains (1) summary
    cl25732
    Location:208594
    SMC_N; RecF/RecN/SMC N terminal domain
  2. NM_018017.4NP_060487.2  coiled-coil domain-containing protein 186 isoform 1

    See identical proteins and their annotated locations for NP_060487.2

    Status: VALIDATED

    Source sequence(s)
    AI672382, AK024739, AK094498, AL834368, BC030557, BX537964, BX643041
    Consensus CDS
    CCDS7587.1
    UniProtKB/Swiss-Prot
    Q7Z3E2
    Related
    ENSP00000358293.3, ENST00000369287.8
    Conserved Domains (1) summary
    cl25732
    Location:208594
    SMC_N; RecF/RecN/SMC N terminal domain
  3. NM_153249.1NP_694981.1  coiled-coil domain-containing protein 186 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK092620, BC030557
    Consensus CDS
    CCDS81506.1
    UniProtKB/Swiss-Prot
    Q7Z3E2
    UniProtKB/TrEMBL
    A0A0C4DFU7
    Related
    ENSP00000358291.3, ENST00000369285.7

RNA

  1. NR_135815.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC022023, AI672382, AK024739, AK094498, BC030557, BC103504, BX537964

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    114120862..114174255 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011539915.3XP_011538217.1  coiled-coil domain-containing protein 186 isoform X1

    Conserved Domains (1) summary
    cl19219
    Location:247332
    DUF342; Protein of unknown function (DUF342)
  2. XM_011539916.3XP_011538218.1  coiled-coil domain-containing protein 186 isoform X2

    Conserved Domains (1) summary
    cl19219
    Location:323409
    DUF342; Protein of unknown function (DUF342)
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