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SOBP sine oculis binding protein homolog [ Homo sapiens (human) ]

Gene ID: 55084, updated on 4-Nov-2018

Summary

Official Symbol
SOBPprovided by HGNC
Official Full Name
sine oculis binding protein homologprovided by HGNC
Primary source
HGNC:HGNC:29256
See related
Ensembl:ENSG00000112320 MIM:613667; Vega:OTTHUMG00000015312
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
JXC1; MRAMS
Summary
The protein encoded by this gene is a nuclear zinc finger protein that is involved in development of the cochlea. Defects in this gene have also been linked to intellectual disability. [provided by RefSeq, Mar 2011]
Expression
Broad expression in brain (RPKM 6.2), ovary (RPKM 3.5) and 21 other tissues See more
Orthologs

Genomic context

See SOBP in Genome Data Viewer
Location:
6q21
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 6 NC_000006.12 (107490104..107661309)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (107811317..107982513)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene RNA, U6 small nuclear 1299, pseudogene Neighboring gene decaprenyl diphosphate synthase subunit 2 Neighboring gene ribosomal protein S24 pseudogene 12 Neighboring gene Scm polycomb group protein like 4 Neighboring gene SEC63 homolog, protein translocation regulator Neighboring gene RNA, U6 small nuclear 437, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10159

Gene Ontology Provided by GOA

Function Evidence Code Pubs
SUMO polymer binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cochlea development IEA
Inferred from Electronic Annotation
more info
 
cognition IMP
Inferred from Mutant Phenotype
more info
PubMed 
inner ear morphogenesis IEA
Inferred from Electronic Annotation
more info
 
locomotory behavior IEA
Inferred from Electronic Annotation
more info
 
sensory perception of sound IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
sine oculis-binding protein homolog
Names
jackson circler protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_028200.1 RefSeqGene

    Range
    5001..176197
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_018013.3NP_060483.3  sine oculis-binding protein homolog

    See identical proteins and their annotated locations for NP_060483.3

    Status: REVIEWED

    Source sequence(s)
    AL096816, AL121957, BC014859, BC113966, BM684094, BX442875
    Consensus CDS
    CCDS43488.1
    UniProtKB/Swiss-Prot
    A7XYQ1
    UniProtKB/TrEMBL
    Q24K27
    Related
    ENSP00000318900.5, OTTHUMP00000198925, ENST00000317357.9, OTTHUMT00000041693
    Conserved Domains (1) summary
    pfam15279
    Location:224524
    SOBP; Sine oculis-binding protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p12 Primary Assembly

    Range
    107490104..107661309
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005267042.4XP_005267099.1  sine oculis-binding protein homolog isoform X2

    Conserved Domains (1) summary
    pfam15279
    Location:243543
    SOBP; Sine oculis-binding protein
  2. XM_005267041.4XP_005267098.1  sine oculis-binding protein homolog isoform X1

    See identical proteins and their annotated locations for XP_005267098.1

    Conserved Domains (1) summary
    pfam15279
    Location:275575
    SOBP; Sine oculis-binding protein
  3. XM_011535920.2XP_011534222.1  sine oculis-binding protein homolog isoform X1

    See identical proteins and their annotated locations for XP_011534222.1

    Conserved Domains (1) summary
    pfam15279
    Location:275575
    SOBP; Sine oculis-binding protein
  4. XM_011535921.2XP_011534223.1  sine oculis-binding protein homolog isoform X3

    Conserved Domains (1) summary
    pfam15279
    Location:237537
    SOBP; Sine oculis-binding protein
  5. XM_017010991.1XP_016866480.1  sine oculis-binding protein homolog isoform X4

  6. XM_017010994.1XP_016866483.1  sine oculis-binding protein homolog isoform X4

  7. XM_011535923.2XP_011534225.1  sine oculis-binding protein homolog isoform X5

    Conserved Domains (1) summary
    pfam15279
    Location:1265
    SOBP; Sine oculis-binding protein
  8. XM_017010993.1XP_016866482.1  sine oculis-binding protein homolog isoform X4

  9. XM_017010992.1XP_016866481.1  sine oculis-binding protein homolog isoform X4

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