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SOBP sine oculis binding protein homolog [ Homo sapiens (human) ]

Gene ID: 55084, updated on 5-Aug-2022

Summary

Official Symbol
SOBPprovided by HGNC
Official Full Name
sine oculis binding protein homologprovided by HGNC
Primary source
HGNC:HGNC:29256
See related
Ensembl:ENSG00000112320 MIM:613667; AllianceGenome:HGNC:29256
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
JXC1; MRAMS
Summary
The protein encoded by this gene is a nuclear zinc finger protein that is involved in development of the cochlea. Defects in this gene have also been linked to intellectual disability. [provided by RefSeq, Mar 2011]
Expression
Broad expression in brain (RPKM 6.2), ovary (RPKM 3.5) and 21 other tissues See more
Orthologs
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Genomic context

See SOBP in Genome Data Viewer
Location:
6q21
Exon count:
11
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (107490117..107661306)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (108669050..108840201)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (107811321..107982510)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene decaprenyl diphosphate synthase subunit 2 Neighboring gene ribosomal protein S24 pseudogene 12 Neighboring gene uncharacterized LOC124901366 Neighboring gene Sharpr-MPRA regulatory region 6907 Neighboring gene uncharacterized LOC124901367 Neighboring gene Scm polycomb group protein like 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10159

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables SUMO polymer binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in animal organ development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cochlea development IEA
Inferred from Electronic Annotation
more info
 
involved_in cognition IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in inner ear morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in locomotory behavior IEA
Inferred from Electronic Annotation
more info
 
involved_in sensory perception of sound IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
sine oculis-binding protein homolog
Names
jackson circler protein 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_028200.2 RefSeqGene

    Range
    5005..176194
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_018013.4NP_060483.3  sine oculis-binding protein homolog

    See identical proteins and their annotated locations for NP_060483.3

    Status: REVIEWED

    Source sequence(s)
    AL096816, AL121957, BC014859, BC113966, BM684094, BX442875
    Consensus CDS
    CCDS43488.1
    UniProtKB/Swiss-Prot
    A7XYQ1, Q8N2B2
    UniProtKB/TrEMBL
    Q24K27
    Related
    ENSP00000318900.5, ENST00000317357.10
    Conserved Domains (1) summary
    pfam15279
    Location:224524
    SOBP; Sine oculis-binding protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    107490117..107661306
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011535920.3XP_011534222.1  sine oculis-binding protein homolog isoform X1

    See identical proteins and their annotated locations for XP_011534222.1

    Conserved Domains (1) summary
    pfam15279
    Location:275575
    SOBP; Sine oculis-binding protein
  2. XM_047418962.1XP_047274918.1  sine oculis-binding protein homolog isoform X2

  3. XM_047418963.1XP_047274919.1  sine oculis-binding protein homolog isoform X3

    UniProtKB/Swiss-Prot
    Q8N2B2
  4. XM_047418964.1XP_047274920.1  sine oculis-binding protein homolog isoform X4

  5. XM_047418965.1XP_047274921.1  sine oculis-binding protein homolog isoform X5

  6. XM_047418968.1XP_047274924.1  sine oculis-binding protein homolog isoform X6

  7. XM_047418967.1XP_047274923.1  sine oculis-binding protein homolog isoform X5

  8. XM_047418966.1XP_047274922.1  sine oculis-binding protein homolog isoform X5

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    108669050..108840201
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)