Format

Send to:

Choose Destination

TMEM45A transmembrane protein 45A [ Homo sapiens (human) ]

Gene ID: 55076, updated on 13-Mar-2020

Summary

Official Symbol
TMEM45Aprovided by HGNC
Official Full Name
transmembrane protein 45Aprovided by HGNC
Primary source
HGNC:HGNC:25480
See related
Ensembl:ENSG00000181458 MIM:616928
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DERP7; DNAPTP4
Expression
Biased expression in skin (RPKM 215.6), liver (RPKM 25.9) and 2 other tissues See more
Orthologs

Genomic context

See TMEM45A in Genome Data Viewer
Location:
3q12.2
Exon count:
10
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (100492619..100577446)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (100211463..100296297)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene translocase of outer mitochondrial membrane 70 Neighboring gene leukemia NUP98 fusion partner 1 Neighboring gene adhesion G protein-coupled receptor G7 Neighboring gene glia maturation factor beta pseudogene 1 Neighboring gene trafficking from ER to golgi regulator

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10134

Gene Ontology Provided by GOA

Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane protein 45A
Names
DNA polymerase-transactivated protein 4
dermal papilla derived protein 7

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001363876.2NP_001350805.1  transmembrane protein 45A isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC128693
    Consensus CDS
    CCDS87113.1
    Related
    ENSP00000385089.1, ENST00000403410.5
    Conserved Domains (1) summary
    pfam04819
    Location:139256
    DUF716; Family of unknown function (DUF716)
  2. NM_018004.3NP_060474.1  transmembrane protein 45A isoform 2

    See identical proteins and their annotated locations for NP_060474.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AC128693, AY450392, BG205309
    Consensus CDS
    CCDS2937.1
    UniProtKB/Swiss-Prot
    Q9NWC5
    Related
    ENSP00000319009.4, ENST00000323523.8
    Conserved Domains (1) summary
    pfam04819
    Location:123240
    DUF716; Family of unknown function (DUF716)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    100492619..100577446
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005247569.2XP_005247626.1  transmembrane protein 45A isoform X1

    See identical proteins and their annotated locations for XP_005247626.1

    UniProtKB/TrEMBL
    J3KQ06
    Conserved Domains (1) summary
    pfam04819
    Location:139256
    DUF716; Family of unknown function (DUF716)
  2. XM_024453614.1XP_024309382.1  transmembrane protein 45A isoform X2

    Conserved Domains (1) summary
    pfam04819
    Location:123240
    DUF716; Family of unknown function (DUF716)
  3. XM_024453615.1XP_024309383.1  transmembrane protein 45A isoform X2

    Conserved Domains (1) summary
    pfam04819
    Location:123240
    DUF716; Family of unknown function (DUF716)
Support Center